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ECP's extensive clinical record, as well as a considerable improvement in the understanding of the mechanism that underlies its efficacy, opens potential novel strategies for the treatment of cancer, GVHD, transplant rejection, and autoimmunity. The low side effect profile of this therapy has made
Depressive thoughts have been apparent since the origins of humanity. References to depressive thoughts can be found in philosophical writings and other literature since antiquity. They were always approached in a religious or medical way, with arguments for a mix of psychological and mystical
The development of useful and accurate biomarkers for predicting outcomes of food based interventions is becoming more and more important, given the emphasis being placed on ingredients in foods contributing to disease risk reduction and optimal health promotion. With the human genome now laid bare,
Blood transfusion is made possible principally by use of donated homologous components that - in turn - can be perceived as sources of danger by recipients. This may create an innate immune response dominated by inflammation, especially when transfusion is repeated. Residual leukocytes in blood
METHODS
This overview of the evolution of drug development and the tools utilized by pharmacologists to ensure drug safety and efficacy provides solid insight into the drug development process, the potential for drug interactions and the difference between drugs and non-drug "natural"
The subject of this lecture has been chosen in relation to the contribution that Professor H Alessandri made in the first half of this century, as an outstanding clinician in the professional, humanistic and ethical development of generations of physicians in this country. This lecture is divided in
Brunfelsia genus is traditionally utilized in popular medicine due to its antibacterial and antifungal properties to name but a few. However, studies on the antimicrobial activity of Brunfelsia uniflora flower oleoresin have not been found yet. This study aimed to evaluate the chemical composition
Enteric neuropathy is a term indicating an impairment of the innervation supplying the gastrointestinal tract. The clinical phenotypes of the enteric neuropathies are the 'tip of the iceberg' of severe functional digestive diseases, such as intestinal pseudo-obstruction syndromes (e.g., chronic