4 резултати
This invention relates to a novel use of IL-1.beta.-ligand/IL-1 receptor disrupting compounds (herein referred to as "IL-1beta Compounds"); such as small molecular compounds disrupting IL-1.beta. ligand-IL-1 receptor interaction, IL-1.beta. antibodies or IL-1 receptor antibodies, e.g. IL-1.beta.
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to a novel genomic DNA sequence (MEFV) encoding a protein (pyrin) associated with familial Mediterranean fever (FMF). More specifically, the invention relates to the isolation and characterization of MEFV, and the
BACKGROUND
1. Field of the Invention
The invention relates to methods of using interleukin-1 (IL-1) antagonists to treat autoinflammatory diseases, such as, for example, including familial mediterranean fever (FMF), NOMID/CINCA, Muckle-Wells Syndrome, FCAS, and tumour necrosis factor
BACKGROUND
1. Field of the Invention
The invention relates to methods of using interleukin-1 (IL-1) antagonists to treat autoinflammatory diseases, such as, for example, including familial mediterranean fever (FMF), NOMID/CINCA, Muckle-Wells Syndrome, FCAS, and tumor necrosis factor