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BACKGROUND
Patients with chronic low back pain (cLBP) have high rates of comorbid psychiatric disorders, mainly depression. Recent evidence suggests that depressive symptoms and pain, as interacting factors, have an effect on the circulating levels of inflammatory markers relevant to coronary artery
BACKGROUND
Low back pain, with or without radiculopathy, is an important cause of disability and economic expenditure. However, many patients are not achieving optimal pain control with existing medications. Tumor necrosis factor antagonists (anti-TNFα) could be an alternative drug
OBJECTIVE
To examine the analgesic effect of intradiscal administration of a tumor necrosis factor-αα (TNF-α) inhibitor in patients with discogenic low back pain (LBP).
METHODS
Prospective, randomized study.
METHODS
Department of Orthopaedic Surgery, Chiba (Japan) University
METHODS
Immunohistochemistry for tumor necrosis factor (TNF) and protein gene product (PGP) 9.5 in vertebral endplates of patients with discogenic low back pain and Modic Type 1 or Type 2 endplate changes on MRI.
OBJECTIVE
To examine whether inflammatory cytokines and nerve in-growth into the
METHODS
Several recent studies suggest a high-intensity zone (HIZ) within the posterior annulu of lumbar intervertebral disc seen on T2-weighted magnetic resonance (MR) images represents the inflammation in the annulus, an annular tear, and/or vascular granulation tissue. It has not be reported yet
Background. Deceptive low back and buttock pain, especially at night, is often the main subjective symptom in necrosis of the femoral head. During this period, limitations of the final phase of the range of hip movement (especially inward rotation and abduction) constitute an objective symptom.
Low back pain and/or pain radiating to one or both lower limbs can result from causes other than intervertebral disc disease. Recently three patients presented with low back pain radiating down the legs. When CT examination of the lumbar spine proved unrewarding, magnetic resonance imaging (MRI) was
BACKGROUND
The HELLP-syndrome is a rare complication to pregnancy and a potential fatal condition.
METHODS
We report such a case in a 32-year-old para 2, gravida 1 woman with no known risk factors. A lower transverse uterotomy was performed at 29 weeks and 6 days' gestation based on an indication of
This case report is of a 60-year-old man with left hip avascular necrosis that initially was diagnosed as low back pain syndrome.
Adrenal necrosis, a rare life threatening complication of antiphospholipid syndrome, is difficult to diagnose during pregnancy. We report the case of a 33-year-old woman with bilateral adrenal necrosis which started during the third trimester of her second pregnancy. Antiphospholipid syndrome had
OBJECTIVE
We identified several problems associated with percutaneous lumbar disc decompression (PLDD) based on a study of patients who required salvage operations for complications after undergoing PLDD at an outside institution.
BACKGROUND
PLDD has been performed as a new treatment for
BACKGROUND
Conventional radiologic modalities provide details only about the anatomic aspect of the various structures of the spine. Frequently the structures that show abnormal morphology may not be the cause of low back pain (LBP). Functional imaging in the form of bone scan along with single
OBJECTIVE
To address the challenges for trialing with elderly and the lacking of valid sham/placebo control, a randomized crossover pilot study is designed and its feasibility on elderly subjects is evaluated.
METHODS
A pilot randomized crossover study was conducted with hydrocollator-based hot pack
Infective endocarditis may have different clinical manifestations that result from involvement of different organ systems. These include heart murmur, valvular bacterial vegetation, arterial emboli induced hematuria, conjunctival petechiae, subcutaneous Janeway's spots and Osler's nodes.