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Detection of hypermethylated spastic paraplegia-20 in stool samples of patients with colorectal cancer.

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BACKGROUND Analysis of aberrant hypermethylation in stool DNA might provide a novel strategy for noninvasive detection of colorectal cancer. OBJECTIVE To explore the feasibility of detecting hypermethylation in Spastic paraplegia-20 promoter as a stool-based DNA marker for detection of colorectal

Paraplegia as an initial manifestation of pancreatic cancer.

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Paraplegia can be an initial manifestation of pancreatic cancer, although extremely rare.

Experimental study of paraplegia caused by spinal tumors: an animal model of spinal tumors created by transplantation of VX2 carcinoma.

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BACKGROUND Little is known about the mechanism of the paraplegia produced by metastatic spinal tumors, although the quality of life of patients with paraplegia caused by malignant tumors depends to a great extent on treatment of the paraplegia. We previously established an experimental model of

[Paraplegia caused by extradural spinal hematoma after radical pulmonary lobectomy in cancer].

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The authors report a case of spinal cord complication after surgery for lung cancer. Amongst the 12 cases published in the literature, only one reports spinal cord ischaemia secondary to a compressive mechanism by spinal extradural haematoma. In the present case, due to an identical mechanism,

Paraplegia following spinal anesthesia in a patient with an undiagnosed metastatic spinal tumor.

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Although extremely rare, paraplegia can be a complication following spinal anesthesia if the patient has a previously unrecognized spinal tumor. We describe a 75-year-old male patient who underwent retrograde ureteroscopic examination under spinal anesthesia. He developed complete paraplegia 24

Carcinoid tumor mistaken for persistent neurogenic bowel symptoms in a patient with paraplegia: a case report.

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Neurogenic bowel in spinal cord injury (SCI) can present with constipation and diarrhea as ongoing problems. Usually, these manifestations are adequately controlled with modification in the bowel program. When these symptoms persist, other causes should be considered. This case report describes a

Delayed-Onset Paraplegia Due to Spinal Cord Infarction After Repeated Tumor Excision Surgeries of the Thoracic Spine.

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Tumor excision surgeries of the spine present a distinct challenge regarding the maintenance of spinal cord blood supply because they often require preoperative embolization of segmental arteries, ligation of the corresponding nerve roots, and circumferential exposure of the dural sac. The authors

Postoperative paraplegia as a result of undiagnosed primitive neuroectodermal tumor, not epidural analgesia.

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Postoperative paraplegia is a rare complication after epidural analgesia and often occurs with spinal hematoma or cord injury. We present the case of a 16-year-old girl who suffered from a tumor mass in the neck and abdomen who underwent gynecologic operation. Preoperatively, liver metastasis was

Acute paraplegia after the initiation of anti-tumour necrosis factor-alpha therapy for Crohn's disease.

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Therapies aimed at inhibiting tumour necrosis factor are currently successfully administered to an increasing number of patients with autoimmune diseases. Infliximab has been approved to induce and maintain remission in Crohn's disease and fistulizing Crohn's disease. We report a case of acute-onset

Paraplegia following intercostal nerve neurolysis with alcohol and thoracic epidural injection in lung cancer patient.

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The goal of cancer treatment is generally pain reduction and function recovery. However, drug therapy does not treat pain adequately in approximately 43% of patients, and the latter may have to undergo a nerve block or neurolysis. In the case reported here, a 42-year-old female patient with lung

Detection of aberrant hypermethylated spastic paraplegia-20 as a potential biomarker and prognostic factor in gastric cancer.

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The aim of this study was to evaluate hypermethylation of the spastic paraplegia-20 promoter as a potential biomarker and prognostic factor in gastric cancer. Four human gastric cancer cell lines, 41 primary gastric cancer tissue samples and corresponding peripheral blood samples, and blood samples

Postoperative paraplegia after resection of a giant posterior mediastinal tumour. Importance of the blood supply in the upper spinal cord.

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A 10-cm diameter tumour was revealed in the left upper posterior mediastinum in a 15-year-old female. After exclusion of the possibility of a dumbbell tumour and confirmation of a ganglioneurinoma, an encapsulated, but vascularised tumour was removed via a left posterolateral thoracotomy from the

Dumbbell-type spinal solitary fibrous tumor with paraplegia.

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Solitary fibrous tumors are rare tumors that most commonly arise in the pleura. This article describes a case of a large dumbbell-shaped solitary fibrous tumor of the thoracic spine that was causing partial paraplegia. The patient was a 75-year-old woman who presented with swelling of the upper back

Brown tumor in secondary hyperparathyroidism causing acute paraplegia.

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The first known case of a "brown tumor" associated with secondary hyperparathyroidism causing paraplegia is described. A 69-year-old white woman with chronic renal failure due to hypertension was admitted for back pain, and while she was under observation, paraplegia developed. A complete block was

Brown tumor of the spine and progressive paraplegia in a hemodialysis patient.

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METHODS Case report. OBJECTIVE To describe the radiographic features and management of spinal brown tumor and to document tumor mineralization after parathyroidectomy. BACKGROUND Brown tumors are classic skeletal manifestations of hyperparathyroidism usually seen in severe forms. They are

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