3 резултати
In Proteus mirabilis, a putative phenylalanine decarboxylase (DisA) acts in a regulatory pathway to inhibit class 2 flagellar gene expression and motility. In this study, we demonstrate that DisA expression in Escherichia coli blocked motility and resulted in a 50-fold decrease in the expression of
In this study, we identified a transposon insertion in a novel gene, designated disA, that restored swarming motility to a putrescine-deficient speA mutant of Proteus mirabilis. A null allele in disA also increased swarming in a wild-type background. The DisA gene product was homologous to amino
The disA gene encodes a putative amino acid decarboxylase that inhibits swarming in Proteus mirabilis. 5' rapid amplification of cDNA ends (RACE) and deletion analysis were used to identify the disA promoter. The use of a disA-lacZ fusion indicated that FlhD(4)C(2), the class I flagellar master