8 резултати
OBJECTIVE
To investigate whether a transient outward potassium current exists in children hypertrophy ventricular myocytes and to characterize its basic electrophysiological properties.
METHODS
Currents were recorded using whole-cell patch-clamp technique from enzymatically isolated ventricualr
The effectiveness of systemic deep hypothermia for myocardial protection was evaluated retrospectively in 36 consecutive children who underwent total correction of tetralogy of Fallot in the four-year period 1980 to 1984. Moderate hypothermia combined with potassium-induced cold cardioplegia and
Beginning in July 1977, cold potassium-induced cardioplegia has been used in 60 consecutive patients undergoing correction of congenital heart defects in whom the aorta was cross clamped. Ages ranged from 4 weeks to 18 years (mean 5.8 years); 40 percent were less than 24 months of age. Surgery
This article describes the use of warm cardioplegia in paediatric surgery. Warm blood enriched with potassium was injected every 15 minutes during aortic clamping in 770 operations. The efficacy and quality of this technique were assessed by the return of cardiac electrical activity, troponin I
Myocardial protection was evaluated in 2 groups of 5 infants each undergoing correction of either tetralogy of Fallot (TOF) or subcristal ventricular septal defect (VSD). In group A, profound hypothermia and total circulatory arrest (PHTCA) was utilized. In group B, profound hypothermia and total
Cold potassium cardioplegia was used in 78 consecutive patients undergoing correction of complex congenital heart disease between 1977 and 1982. Ages ranged from 4 weeks to 21 years (mean 6.7 years). The anatomical diagnoses were: tetralogy of Fallot (33), common AV canal (12), pulmonary atresia
Rhythm disturbances that develop after pediatric surgery for heart disease significantly increase mortality and morbidity risk. The aim of this study was to determine incidence rates of different arrhythmias and identify risk factors for these disturbances in this patient group. The study involved
Preservation and development of life depend on the adequate segregation of sister chromatids during mitosis and meiosis. This process is ensured by the cohesin multi-subunit complex. Mutations in this complex have been associated with an increasing number of diseases, termed cohesinopathies. The