5 резултати
TECHNICAL FIELD
The invention is directed at certain ornithine and lysine derivatives which are selective, mechanism-based inactivators of neuronal isoform of nitric oxide synthase and selective inhibitors of nitric oxide synthase.
BACKGROUND OF THE INVENTION
Nitric oxide synthase (NOS) catalyzes
FIELD OF THE INVENTION
This invention relates to a series of N-substituted oxindoline derivatives. In particular, this invention relates to N-substituted oxindoline derivatives that are N-type voltage-gated calcium channel blockers useful for the treatment of a variety of pain conditions including
FIELD OF THE INVENTION
This invention relates to a series of substituted aryl sulfone derivatives. In particular, this invention relates to substituted aryl sulfone derivatives that are N-type voltage-gated calcium channel blockers useful for the treatment of a variety of pain conditions including
BACKGROUND OF THE INVENTION
This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the
BACKGROUND OF THE INVENTION
This invention relates to sulfonyl benzimidazole derivatives. These compounds have selective cannabinoid (CB)2 receptor agonistic activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives