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Maytenus disticha (Hook F.), belonging to the Celastraceae family, is an evergreen shrub, native of the central southern mountains of Chile. Previous studies demonstrated that the total extract of M. disticha (MD) has an acetylcholinesterase inhibitory activity along with growth
Two new β-dihydroagarofuran-type sesquiterpenes (1-2) were isolated and identified from the fruit of Celastrus orbiculatus Thunb, together with seventeen known compounds (3-19). The structures of the isolated new compounds were elucidated based on extensive spectroscopic analyses. The cytotoxic
Dihydroagarofuran sesquiterpenes, which were isolated from Tripterygium wilfordii Hook fil. var. regelii Makino and Euonymus sieboldianus Blume, showed inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). Triptogelin A-1,
Celastrus paniculatus is a traditional medicinal plant with diverse pharmacological activities. To identify its bioactive constituents, three new β-dihydroagarofuranoid sesquiterpenes were isolated from the whole plant, of which the major constituent is
Two new β-dihydroagarofuran-type sesquiterpenes 1β,2α,6α,8β,15- pentaacetoxy- 9α-benzoyloxy- β-dihydroagarofuran (1) and 1β,2β,6α,15-tetraacetoxy-9β-benzoyloxy- β-dihydroagarofuran (2), together with
Three new sesquiterpene polyol esters with a beta-dihydroagarofuran skeleton, NW12 (1), NW27 (2), and NW31 (4), together with a known compound, NW30 (3), were isolated from the root bark of Celastrus angulatus. Their chemical structures were elucidated by analyses of MS and NMR spectral data.
Twelve new dihydroagarofuran sesquiterpene polyol esters, triptersinines A-L (1-12), and eight known sesquiterpene pyridine alkaloids were isolated from the leaves of Tripterygium wilfordii. Their structures were elucidated on the basis of spectroscopic analyses, including UV, IR, and NMR
Investigation of the organic extracts of the roots of Maytenus vitis-idaea and Maytenus spinosa, collected in the province of Salta, Argentina, led to isolation of eighteen compounds belonging to several classes. From M. vitis-idaea, eight methylenequinone celastroids (1-8) were isolated, four of