10 үр дүн
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to methods and compositions for targeting the vasculature of solid tumors using immunological and growth factor-based reagents. In particular aspects, antibodies carrying diagnostic or therapeutic agents
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the field of molecular biology and recombinant protein production. More particularly, it concerns gelonin polypeptides with decreased immunogenicity and cell-targeting constructs comprising said less
BACKGROUND
1. Field of the Invention
The present invention relates generally to the field of immunoconjugates and, more particularly, to the use of immunoconjugates in the diagnosis and treatment of cancer. The invention also relates to the treatment of breast and cervical carcinoma with cytotoxic
BACKGROUND OF THE INVENTION
1. Field of the Invention
The instant invention is a novel method for treating tumors with a toxin. More specifically, the present method involves preliminarily immunizing a patient with a toxin vaccine containing a cytotoxic cancerostatic toxin or toxin surrogate to
BACKGROUND OF THE INVENTION
1. Field of the Invention
The instant invention is a novel method for treating tumors with a toxin. More specifically, the present method involves preliminarily immunizing a patient with a toxin vaccine containing a cytotoxic cancerostatic toxin or toxin surrogate to
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and analogs, some of which
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
FIELD OF THE INVENTION
The present invention generally relates to methods for sterilizing animals and to methods for medically treating certain sex hormone related diseases such as, for example, cancer of the breast or prostate. More particularly, this invention relates to sterilization and medical
BACKGROUND
The present invention relates, in general, to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to polynucleotides encoding ribosome-inactivating proteins, to polynucleotides encoding analogs of ribosome-inactivating proteins
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to the fields of cancer research and targeted therapy. More specifically, the present invention relates to fusion constructs comprising an isoform of vascular endothelial growth factor and uses of such