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Malignant middle cerebral artery infarction (MMCI) has a fatality rate of up to 80%, due to massive brain edema, increased intracranial pressure, and cerebral herniation. The herniation-induced death usually occured during the first week, despite aggressive osmotherapy with mannitol or hypertonic
Participants will have all evaluations related to metabolic complications performed in the University of Iowa Clinical Research Unit (CRU) or in the EndoPAT laboratory located in Room 269 GH. For all visits, weights will be measured without shoes, in light clothing, using an electronic scale that
Cardiovascular disease remains a leading cause of death in North America (1). Uncontrolled platelet activation, adhesion and aggregation initiated by vessel wall plaque rupture are thought to be responsible for acute vascular occlusion in many situations (2-5). Although many platelet inhibition