Хуудас 1 -аас 16 үр дүн
ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
ADDITIONAL DISCLOSURES
Additional disclosures relating to the instant application may be found in "Compositions And Methods Of Use Of Phorbol Esters" U.S. patent application Ser. No. 12/023,753, filed Jan. 31, 2008, to Richard L. Chang, et al, which claims priority benefit of U.S. Provisional Patent
BRIEF DESCRIPTION OF THE INVENTION
The invention relates to treating neoplastic disease such as leukemia and increasing the white blood cell counts in patients suffering from neoplastic diseases or undergoing chemotherapy by a method which comprises administering parenterally to patients an
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method of inhibiting protein kinase C function and to compounds and compositions suitable for use in such a method.
2. Background Information
In mouse skin, phorbol esters exert tumor promoting, inflammatory,
FIELD OF THE INVENTION
The present invention relates to a method of treating a solid tumor, and in particular, to a method involving hypoxic stress as one component and protein kinase C activation as another component.
REFERENCES
Cook, P. F., et al., Biochem. 21: 5794-5799 (1982).
Culver, K., et
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
TECHNICAL FIELD
The present invention relates generally to the medicinal use of phorbol esters.
BACKGROUND
Plants have historically served many medicinal purposes. The World Health Organization (WHO) estimates that 4 billion people, 80% of the world population, presently use herbal medicine for some
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a method of inhibiting protein kinase C function and to compounds and compositions suitable for use in such a method.
2. Background Information
In mouse skin, phorbol esters exert tumor promoting, inflammatory,
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to isolated proteins or peptides useful for inhibition of matrix metalloproteinases. Specifically, this invention relates to a novel protein, isolated from conditioned media of cultured human tumor cells, which binds with
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to inhibitors of nuclear transcription factor NF-.kappa.B, and the use of these inhibitors in the treatment of pathological conditions in humans. Specifically, the present invention relates to the
TECHNICAL FIELD OF THE INVENTION
This invention relates to lymphotoxin-.beta., a lymphocyte membrane-type polypeptide. Lymphotoxin-.beta., also referred to as p33, has been identified on the surface of T lymphocytes, T cell lines, B cell lines and lymphokine-activated killer cells.
This invention
TECHNICAL FIELD OF THE INVENTION
This invention relates to lymphotoxin-.beta., a lymphocyte membrane-type polypeptide. Lymphotoxin-.beta., also referred to as p33, has been identified on the surface of T lymphocytes, T cell lines, B cell lines and lymphokine-activated killer cells.
This invention
TECHNICAL FIELD OF THE INVENTION
This invention relates to lymphotoxin-.beta., a lymphocyte membrane-type polypeptide. Lymphotoxin-.beta., also referred to as p33, has been identified on the surface of T lymphocytes, T cell lines, B cell lines and lymphokine-activated killer cells.
This invention