20 women with breast cancer with vaginal laser treatment

20 women with breast cancer with vaginal probe, no active laser rays

20 women with endometrial cancer with vaginal laser treatment

20 women with endometrial cancer with vaginal probe, no active laser rays

20 women with overactive bladder with vaginal laser treatment

20 women with overactive bladder with vaginal probe, no active laser rays

Laser-Induced Scar

Breast Cancer

Endometrial Cancer

Menopause

Vaginal Atrophy

Bladder, Overactive

Fractional CO 2 laser system (SmartXide 2 V 2 LR,DEKA, Florence, Italy), using the following setting: dot power 30 watt, dwell time 1000 μ s, dot spacing 1000 μ m and the smart stack parameter from 1 to 3. The laser beam is provided using a vaginal probe, which is gently inserted up to the top of the vaginal canal and subsequently withdrawn and rotated in order to provide a complete treatment of the vaginal wall. At the level of the vaginal introitus, the dot power is decreased to 20 watt 27 . A treatment cycle includes three laser applications (every 4 weeks). The procedure is performed in the outpatient clinic and does not require any specific preparation (e.g. analgesia/anesthesia).

Vaginal laser treatment

sham

FractionalCO 2 laser system (SmartXide 2 V 2 LR,DEKA, Florence, Italy), using the following setting: dot power 30 watt, dwell time 1000 μ s, dot spacing 1000 μ m and the smart stack parameter from 1 to 3. The laser beam is provided using a vaginal probe, which is gently inserted up to the top of the vaginal canal and subsequently withdrawn and rotated in order to provide a complete treatment of the vaginal wall. At the level of the vaginal introitus, the dot power is decreased to 20 watt 27 . A treatment cycle includes three laser applications (every 4 weeks). The procedure is performed in the outpatient clinic and does not require any specific preparation (e.g. analgesia/anesthesia).

laser system

Gynecology Dept. Herning Hospital

Laser Treatment of Genito-urinary Syndrome in Women

Laser Treatment of Genito-urinary Syndrome in Women With Breast and Endometrial Cancer and Menopausal Women

10-cm VAS to measure the overall satisfaction with vaginal symptoms, where the left extreme of the scale indicated ' the worst level of satisfaction ' and the right indicated ' the best level of satisfaction

Qualitative analysis of the microscopic and ultrastructural aspects of the collagenic and elastic components of the matrix is performed. A specific image analysis with computerized morphometry is performed to demonstrate the specific action of CO2 laser and possibly to correlate the modifications of the ultrastructural pattern with specific molecular modifications. We also consider the fine cytological aspects of connective tissue proper cells, particularly fibroblasts, under the conditions of the specific laser stimulation.

a sterile swab is inserted into the vaginal canal and a sample obtained from the posterior fornix of the vagina. Vaginal samples are placed in a transport gel (Stuart). pH indicator strips (MColorpHastTM, Merck, Germany) are applied against the lateral vaginal wall using sterile forceps, followed by a vaginal lavage for wet mount. Smears from vaginal samples are placed on a glass slide, observed under microscope for Trichomonas vaginalis and Candida species and stained afterwards according to standard Gram stain procedure. Cultures for aerobic and anaerobic bacteria species are performed, using MacConkey agar, blood agar, Sabouraud dextrose agar, chocolate agar as culture media, focusing on bacteria with potential clinical impact (e.g. aerobic vaginitis39, UTIs, vaginal candidiasis).

Finn Friis Lauszus

Senior Consultant, Research Specialist

Herning Hospital

Four Groups of women randomized for thre months to either laser og sham treatment

Laser probe perform similar noise and movement without providing rays

all patients in both study and control groups will undergo thermal camera photo of the tonsils by Flir HM series

Fever

Sore Throat

The patient will be photographed twice by directing the camera externally to each tonsil from below the mandibular angle

Thermal camera by Flir -HM series.

Primary Care Clinic of Clalit Health Services

Thermographic Characteristics of Sore Throat by Thermographic Camera

Correlation between tonsillitis characterized by redness of tonsils and/or pharynx, exudates on tonsils, petechiae of the palate and temperature of the tonsils as measured by the thermal camera photo.

purpura/breast neoplasms

Laser Treatment of Genito-urinary Syndrome in Women

Thermographic Characteristics of Sore Throat by Thermographic Camera

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