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tetrandrine/hypoxia

Холбоосыг санах ойд хадгалдаг
НийтлэлЭмнэл зүйн туршилтПатент
13 үр дүн

[Effect of tetrandrine on pulmonary vascular morphology in rats with hypoxia pulmonary hypertension].

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
To investigate the effect of Tetrandrine on pulmonary vascular morphology in rats with hypoxia pulmonary hypertension. We established the model of hypoxia pulmonary hypertension and observed the small pulmonary arterial morphologic changes under light microscope and electron microscope after the

Effects of tetrandrine on changes of NMDA receptor channel in cortical neurons of rat induced by anoxia.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE To study the effects of tetrandrine (Tet) on the changes of NMDA receptor channels in cortical neurons induced by anoxia. METHODS Cell-attached configuration of patch-clamp techniques. Anoxia was produced by perfused cells with 95% N2 + 5% CO2 gassed bath solution. RESULTS During anoxia,

[Effect of tetrandrine on the collagen contents of lungs in rats with chronic hypoxia].

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE To investigate the effect of tetrandrine (Tet) on the collagen contents of lung tissues in rats with chronic hypoxic pulmonary hypertension. METHODS Using colorimetric method after oxidized by chloramine T to determine hydroxyproline contents of lung tissues and extrapulmonary arteries,

Studies on the calcium antagonistic action of tetrandrine: XIII. Protective effect of tetrandrine on myocardial hypoxia and necrosis induced by isoproterenol in rats.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх

Tetrandrine Suppresses Cancer Angiogenesis and Metastasis in 4T1 Tumor Bearing Mice.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
Metastasis remains the most deadly aspect of cancer and still evades direct treatment. Thus, there is a great need to develop new treatment regimens to suppress tumor cells that have escaped surgical removal or that may have already disseminated. We have found that tetrandrine (TET) exhibits

[Effect of tetrandrine on calmodulin activity of lung tissue in rats with hypoxic pulmonary hypertension].

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE The mechanism that tetrandrine (Tet) reduces hypoxic pulmonary hypertension was investigated METHODS 30 Wistar rats were divided into normal control group, pulmonary hypertension group and tetrandrine-treated group. Total calcium conteins and calmodulin activity in lung tissue were

Effects of hypoxia on testosterone release in rat Leydig cells.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
The aim of this study was to explore the effect and action mechanisms of intermittent hypoxia on the production of testosterone both in vivo and in vitro. Male rats were housed in a hypoxic chamber (12% O(2) + 88% N(2), 1.5 l/ml) 8 h/day for 4 days. Normoxic rats were used as control. In an in vivo

[Effect of tetrandrine on expression of bFGF in lung tissue of rat with chronic hypoxic pulmonary hypertension].

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE To evaluate effect of tetrandrine (Tet) on chronic hypoxic pulmonary by observing expression of bFGF in lung tissue of rat with chronic hypoxic pulmonary hypertension. METHODS 30 rats were divided into 3 groups: hypoxia group, hypoxia + Tet group and control group. On the 21st day of

[The acute effect of tetrandrine pulmonary targeting microspheres on hypoxic pulmonary hypertension in rats].

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE To investigate the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and its selective role on pulmonary circulation. METHODS Tet pulmonary targeting microspheres were synthesized by spraying desiccation, the content of tetrandrine in pulmonary

Acute effect of tetrandrine pulmonary targeting microspheres on hypoxic pulmonary hypertension in rats.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
OBJECTIVE To assess the effect of tetrandrine (Tet) pulmonary targeting microspheres on hypoxic pulmonary hypertension and evaluate its selective action on pulmonary circulation. METHODS Twenty rats were exposed to hypoxic conditions for 3 weeks. Ten rats were used as normoxic controls. We

BLOCKADE OF LARGE CONDUCTANCE CA(2+) ACTIVATED K(+) CHANNEL MAY PROTECT NEURONAL CELLS FROM HYPOXIA MIMETIC INSULT AND OXIDATIVE STRESS.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
Previous studies have linked neuronal cell death with changes of intracellular Ca(2+)([Ca(2+)](i)) homeostasis. Such changes of [Ca(2+)](I) has been noticed in various neurodegenerative models. It has also been suggested that K(+)channel, such as large conductance Ca(2+)-activated K(+) channel (BK),

Tetrandrine suppresses lung cancer growth and induces apoptosis, potentially via the VEGF/HIF-1α/ICAM-1 signaling pathway.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
The present study investigated the effect of tetrandrine on lung cancer cell growth and apoptosis, and its possible underlying molecular mechanism. A549 human lung cancer cells were incubated with between 2.5 and 10 µM tetrandrine for 12, 24 and 48 h, following which the effect of tetrandrine on

Tetrandrine cardioprotection in ischemia-reperfusion (I/R) injury via JAK3/STAT3/Hexokinase II.

Зөвхөн бүртгэлтэй хэрэглэгчид л нийтлэл орчуулах боломжтой
Нэвтрэх / Бүртгүүлэх
Tetrandrine (TET), a bisbenzylisoquinoline alkaloid has been used for the treatment of cardiovascular diseases and hypertension. This study was to investigate whether tetrandrine exerts cardioprotection in ischemia-reperfusion (I/R) injury and the mechanisms involved. The cardioprotection effect and
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