Impact of Risk for OSA in Lung Cancer
Sleutelwoorden
Abstract
Omschrijving
The patients who admit the palliative care outpatient clinic of our hospital with the diagnosis of lung cancer (stage 3 and stage 4 non-small cell lung cancer or limited / extensive stage small cell lung cancer) between July 2019-2020 prior to the treatment and the patient who has not yet completed the first-line chemotherapy with a weight loss <10% will be invited to fill the Epworth sleepiness scale and the STOP-BANG questionnaire. Patients' anthropometric measurements (height, weight, BMI, fat-free BMI, neck circumference) will be taken. The treatment outcomes and side-effects in patients with EDS and moderate / high risk for OSA will be compared with patients with low OSA risk. Demographic information (age, gender, smoking history), anthropometric measurements (height, weight, body mass index, fat free body mass index, neck circumference), clinical information (snoring, witnessed apnea, daytime excessive sleep presence of symptoms of symptoms, pulmonary function tests, radiological TNM stages, diagnostic method, diagnosis date, fiberoptic bronchoscopy findings, ECOG performance status, treatment results, treatment-related side effects) laboratory values (complete blood count results albumin, lactate dehydrogenase level) and the results of Epworth sleepiness scale and of STOP-BANG questionnaire will be recorded.
Datums
| Laatst geverifieerd: | 12/31/2019 |
| Eerste ingediend: | 06/20/2019 |
| Geschatte inschrijving ingediend: | 06/27/2019 |
| Eerst geplaatst: | 06/30/2019 |
| Laatste update ingediend: | 01/05/2020 |
| Laatste update geplaatst: | 01/06/2020 |
| Werkelijke startdatum van het onderzoek: | 06/30/2019 |
| Geschatte primaire voltooiingsdatum: | 06/30/2020 |
| Geschatte voltooiingsdatum van het onderzoek: | 06/30/2021 |
Conditie of ziekte
Interventie / behandeling
Other: STOP- BANG Questionnaire and Epworth sleepiness scale
Fase
Armgroepen
| Arm | Interventie / behandeling |
|---|---|
| Moderate/high risk for OSA with EDS All clinical data of the patients who has moderate/high risk for OSA with excessive daytime sleepiness (EDS) will be assessed with statistical methods. | |
| Moderate/high risk for OSA without EDS All clinical data of the patients who has moderate/high risk for OSA without excessive daytime sleepiness(EDS) will be assessed with statistical methods. | |
| Low risk for OSA All clinical data of the patients who has low risk for OSA will be assessed with statistical methods. |
Geschiktheidscriteria
| Leeftijden die in aanmerking komen voor studie | 18 Years Naar 18 Years |
| Geslachten die in aanmerking komen voor studie | All |
| Bemonsteringsmethode | Probability Sample |
| Accepteert gezonde vrijwilligers | Ja |
| Criteria | Inclusion Criteria: - Patients between 18-75 years of age with the diagnosis of lung cancer (stage 3 and 4 non-small cell lung cancer or limited / extensive small cell lung cancer) and who sign the informed consent to participate in the study Exclusion Criteria: - Patients older than 75 years old amd younger than 18 years old - Sedatives / anxiolytic drug users - Neurological or psychiatric disorders - Those who have contradictions for standard chemoradiotherapy (ECOG performance status 3-4) - Stage 1 or stage 2 non-small cell lung cancer patients who may be referred to thoracic surgery - Patients with brain metastasis - People who have a shift work - Vena cava superior syndrome - Alcohol dependence - Malignant airway stenosis - Congestive heart failure (EF <50%) - Patients with chronic renal failure |
Resultaat
Primaire uitkomstmaten
1. STOP-BANG questionnaire [Up to 4 months from the initial diagnosis of lung cancer (the patients who has not initiated or has not finished the first line therapy )]
2. Epworth Sleepiness Scale (ESS) [Up to 4 months from the initial diagnosis of lung cancer (the patients who has not initiated or has not finished the first line therapy will be assessed with Epworth Sleepiness Scale)]
