antiparkinson/versterkte bloedingsneiging

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Interactions between drugs for erectile dysfunction and drugs for cardiovascular disease.

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The association of erectile dysfunction (ED) and cardiovascular disease is well-documented in the literature and both conditions share risk factors. Therefore, it is difficult to distinguish the effect of underlying disease and adverse effects of the drugs and/or interactions between ED drugs and

A study of medial pallidotomy for Parkinson's disease: clinical outcome, MRI location and complications.

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We have studied the effects of unilateral ventral medial pallidotomy in 26 patients with medically intractable Parkinson's disease with marked drug-induced dyskinesias. Preoperatively, all patients were assessed during one 5-day admission according to the Core Assessment Programme for Intracerebral

Barium enema in frail elderly patients.

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BACKGROUND Barium enema (BE) examinations for the investigation of suspected colonic disease are often unsuccessful in elderly patients. OBJECTIVE The purpose of this study was to evaluate the success rate of BE in hospitalized frail elderly patients. METHODS Four hundred and seventy-two elderly

Development of Parkinsonism symptoms immediately after severe head injury.

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This is case report of a young adult male who had developed Parkinsonism symptoms shortly after severe head injury due to accidental fall. This 45-year-old man was diagnosed as multiple hemorrhagic contusions, sub arachnoid hemorrhage and linear skull fracture. After 4 weeks of fall, he developed

Estrogen improves motor disability in parkinsonian postmenopausal women with motor fluctuations.

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OBJECTIVE To test the efficacy, tolerance, and safety of low-dose oral estrogen in postmenopausal women with PD associated with motor fluctuations. BACKGROUND Motor fluctuations in PD may be predictable or unpredictable, and eventually affect most patients after long-term levodopa therapy. Although

Behavioural effects of basal ganglia rho-kinase inhibition in the unilateral 6-hydroxydopamine rat model of Parkinson's disease.

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Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which affects more than six million people in the world. While current available pharmacological therapies for PD in the early stages of the disease usually improve motor symptoms, they cause side effects, such as

Dyskinesias and the subthalamic nucleus.

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Severe dyskinesias or ballism can occur following hemorrhagic events in the subthalamic nucleus (STN), and it has recently been established that the STN plays a major role in the pathophysiology of the motor dysfunction of Parkinson's disease (PD) and that STN inhibition improves parkinsonian

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