The present invention is intended to provide a novel anticancer agent which is effective to a cancer. After administering an agent prepared using burdock fruit extract to a pancreas cancer patient so that a dose of arctigenin was 100 mg or more per day, the tumor reducing effect was observed, and, in addition, lowering of tumor markers was confirmed. The present invention provides an anticancer agent containing arctigenin, wherein a dose of the arctigenin is 100 mg or more per day. In addition, the present invention provides the anticancer agent containing arctigenin and arctiin at a weight ratio of arctigenin/arctiin=0.7 to 1.3.

Kracie Pharma, Ltd.

NATIONAL CANCER CENTER

National University Corporation University of Toyama

National Cancer Center

Anti-cancer agent

PROBLEM TO BE SOLVED A burdock fruit extract containing arctigenin at high content and its production method are provided, and both of which are used for treatment of pancreatic cancer. SOLUTION The burdock fruit extract containing arctigenin at high content by enzymatically converted arctiin into arctigenin with beta-glucosidase, which is an enzyme occurring endogenously in a burdock fruit, and adding ethanol, extracting, concentrating and then freeze-drying or spray drying.

Yamamoto; Keiichi

Okubo; Toshiki

Yomoda; Satoshi

Esumi; Hiroyasu

Miyoshi; Chika

Kadota; Shigetoshi

Japan as Represented by President of National Cancer Center

Burdock fruit extract containing arctigenin at high content and process for producing same

arctiin

kanker

neoplasms

arctiin/kanker

Anti-cancer agent

Burdock fruit extract containing arctigenin at high content and process for producing same

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