butterfly/borstkanker

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A butterfly effect in cancer.

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A point mutation in PIK3CA, the gene encoding the α isoform of class I phosphatidylinositol 3-kinase, induces extensive remodeling of the transcriptome and proteome, resulting in a gene signature that specifically resembles that of the basal subtype, but not other types, of breast cancer.

Enhanced Monarchy Butterfly Optimization Technique for effective breast cancer diagnosis.

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Breast cancer is the biggest curse for the women society in the world since the survival factor of the infected patients is ensured only when it is detected at the early localized stage. The majority of the intelligent schemes proposed for detecting the breast cancer relies on the human skill that

The butterfly effect in cancer: a single base mutation can remodel the cell.

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We have compared the proteome, transcriptome, and metabolome of two cell lines: the human breast epithelial line MCF-10A and its mutant descendant MCF-10A-H1047R. These cell lines are derived from the same parental stock and differ by a single amino acid substitution (H1047R) caused by a single

Cytotoxic responses of carnosic acid and doxorubicin on breast cancer cells in butterfly-shaped microchips in comparison to 2D and 3D culture.

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Two dimensional (2D) cell culture systems lack the ability to mimic in vivo conditions resulting in limitations for preclinical cell-based drug and toxicity screening assays and modelling tumor biology. Alternatively, 3D cell culture systems mimic the specificity of native tissue with better

Biosensing breast cancer cells based on a three-dimensional TIO2 nanomembrane transducer.

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The early diagnosis of breast cancer is crucial for the successful treatment and recovery phases of the patients suffering from the disease. Although mammography is considered the gold standard for diagnosis, it fails to detect some cancers in high-density breasts. In this work, we propose for the

Bioactivities and compositional analyses of Cinnamomum essential oils from Nepal: C. camphora, C. tamala, and C. glaucescens.

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This work examines the biological activity of essential oils of Cinnamomum camphora leaves, C. glaucescens fruit, and C. tamala root from Nepal. The oils were screened for phytotoxic activity against lettuce and perennial ryegrass, brine shrimp lethality, and antibacterial, antifungal, cytotoxic,

Inclusion of heart substructures in the optimization process of volumetric modulated arc therapy techniques may reduce the risk of heart disease in Hodgkin's lymphoma patients.

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Radiotherapy is an effective treatment for Hodgkin's lymphoma (HL), but increases the risk of long term complications as cardiac events and second cancers. This study aimed to reduce the risk of cardiovascular events through an optimization of the dose distribution on heart

Fast nonlinear image reconstruction for scanning impedance imaging.

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Scanning (electrical) impedance imaging (SII) is a novel high-resolution imaging modality that has the potential of imaging the electrical properties of thin biological tissues. In this paper, we apply the reciprocity principle to the modeling of the SII system and develop a fast nonlinear inverse

[Toxidermy mimicking acute chemotherapy-induced lupus erythematosus].

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Acute chemotherapy-induced lupus erythematosus (ALE) is rare. A few cases have been reported in the literature criminalizing capecitabine, paclitaxel and docetaxel. We report the case of a 64-year old female patient without a history of autoimmune diseases or of drug allergy followed up for invasive

Cremophor-induced lupus erythematosus-like reaction with taxol administration: a case report and review of the literature.

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We report the first case of Cremophor EL-induced cutaneous lupus erythematosus-like reaction in a 40-year-old female undergoing treatment for breast cancer. There have been four reported cases of paclitaxel- and four cases of docetaxel-induced cutaneous lupus reactions in the published literature

Palladium(II) complexes with tris(2-carboxyethyl)phosphine, structure, reactions and cytostatic activity.

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Water soluble and air stable P(RCOOH)3 (R=C2H4) (TCEP) is an efficient reducing agent used in biochemistry to break S-S bond in peptides, proteins and other compounds containing S-S bonds. The similarity between the coordination chemistry of Pd(II) and Pt(II) led to the investigations of antitumor

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