citric acid/vermoeidheid

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Effects of Citric Acid and l-Carnitine on Physical Fatigue.

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We examined the effects of citric acid and l-carnitine administration on physical fatigue. In a double-blind, placebo-controlled, 3-way crossover study, 18 healthy volunteers were randomized to oral citric acid (2,700 mg/day), l-carnitine (1,000 mg/day), or placebo for 8 days. The fatigue-inducing

Asynchronous increases in oxidative capacity and resistance to fatigue of electrostimulated muscles of rat and rabbit.

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1. The present study investigates to what extent increases in resistance to fatigue and aerobic oxidative capacity of energy metabolism are correlated in fast-twitch tibialis anterior muscles of rat and rabbit subjected to chronic low-frequency stimulation. 2. Changes in the aerobic oxidative

Serum metabolite profiles of postoperative fatigue syndrome in rat following partial hepatectomy.

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Postoperative fatigue syndrome is a general complication after surgery. However, there is no ''gold standard'' for fatigue assessment due to the lack of objective biomarkers. In this study, a rodent model of postoperative fatigue syndrome based on partial hepatectomy was firstly established and

Mental and physical fatigue-related biochemical alterations.

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OBJECTIVE To confirm fatigue-related biochemical alterations, we measured various parameters just before and after relaxation and fatigue-inducing mental or physical sessions. METHODS Fifty-four healthy volunteers were randomized to perform relaxation and fatigue-inducing mental and physical

Pyruvate and citric acid cycle carbon requirements in isolated skeletal muscle mitochondria.

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Carbohydrate depletion precipitates fatigue in skeletal muscle, but, because pyruvate provides both acetyl-CoA for mainline oxidation and anaplerotic carbon to the citric acid cycle (CAC), the mechanism remains obscure. Thus pyruvate and CAC kinetic parameters were independently quantified in

Changes in taste perception following mental or physical stress.

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Taste perception depends not only on the chemical and physical properties of tastants, but may also depend on the physiological and psychological conditions of those who do the tasting. In this study, the effects of mood state on taste sensitivity was evaluated in humans who were exposed to

A high throughput in vivo assay for taste quality and palatability.

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Taste quality and palatability are two of the most important properties measured in the evaluation of taste stimuli. Human panels can report both aspects, but are of limited experimental flexibility and throughput capacity. Relatively efficient animal models for taste evaluation have been developed,

Importance of purine nucleotide cycle to energy production in skeletal muscle.

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The purpose of this study was to determine the role of the purine nucleotide cycle in aerobic energy production. Rats received either saline or 5-amino-4-imidazolecarboxamide riboside (AICAriboside), a precursor to an inhibitor of adenylosuccinate lyase (AICAR). Muscle tension was quantified during

Influence of intermittent long-term stimulation on contractile, histochemical and metabolic properties of fibre populations in fast and slow rabbit muscles.

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Slow (m.soleus) and fast (m.tibialis anterior) muscles of the rabbit were subjected to indirect long-term intermittent stimulation (3 weeks, 8 hrs daily) with a frequency pattern of 10 imp/sec. Whereas no changes were observed in case of the slow muscle, stimulation induced profound changes in the

Fiber type distribution and maximal activities of enzymes involved in energy metabolism following short-term supramaximal exercise.

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Alterations in enzyme activities involved in muscle energy metabolism and the muscle fiber type distribution were investigated in six subjects, ranging in age from 19-23 years, following short-term, high intensity exercise. Changes in the vastus lateralis muscle were studied prior to exercise and

Fluid replacement drinks during high intensity exercise: effects on minimizing exercise-induced disturbances in homeostasis.

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The purpose of these experiments was to examine the influence of various fluid replacement drinks on exercise-induced disturbances in homeostasis during heavy exercise. Nine trained cyclists performed constant load exercise on a cycle ergometer to fatigue on three occasions with 1-week separating

Emerging opportunities with NMR.

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Several nuclear magnetic resonance (NMR) methods with potential as tools for the study of neuromuscular fatigue are described briefly. 13C MR spectroscopy (MRS) is presented as a means of studying the regulation of substrate (fuel) flux into the citric acid cycle. 23Na and 39K MRS can be used to

[Effect of variation of lemon intake and walking in daily life on various indicators of muscle mass and blood biochemistry in menopausal middle-aged and elderly women].

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OBJECTIVE We examined the factors considered to change body composition and blood biochemistry indicators in menopausal middle-aged and elderly women. These changes result from exercise by walking as part of their daily activities and lemon consumption by women who live on the small islands of the

Effect of triheptanoin on muscle metabolism during submaximal exercise in horses.

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OBJECTIVE To compare effects of corn oil or a 7-carbon fat (triheptanoin) on acylcarnitine, lipid, and carbohydrate metabolism in plasma or muscle of exercising horses. METHODS 8 Thoroughbred geldings. METHODS Horses received isocaloric diets containing 650 mL of oil (triheptanoin or corn oil)/d for

Mental energy: plausible neurological mechanisms and emerging research on the effects of natural dietary compounds.

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Objective: Lack of mental energy is one of the leading reasons adults turn to dietary supplements, with three out of ten supplement users hoping to improve their energy level; even more consume caffeine-containing products for the same reason. Despite this interest from consumers, there is no

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