It relates to an Association of chemical agents, with intended pharmacological action to prevent the risk of infarction and brain hemorrhage caused by the development of the atherosclerotic process and of the homocysteinemia resulting from ageing. It is of the utmost importance to prevent the increase of endogenous homocysteine. High levels of homocysteine in blood, caused by genetical error and further biologic circumstances impart damaging consequences upon the human organism (occlusion of blood vessels, ocular modifications, osteoporosis and nervous system).

Laboratorios Biosintetica LTDA.

Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers

A method and composition are described for reducing the elevated plasma homocysteine level in mammals (humans) by oral administration of a therapeutically effective amount of Allium plants or extracts thereof, preferably garlic, with or without one or more vitamins such as B.sub.6, B.sub.12 and folic acid in an acceptable pharmaceutical carrier. Enhanced effectiveness is achieved with a combination of Allium plants or extracts thereof, preferably garlic, with vitamins such as B.sub.6, B.sub.12 and folic acid. The described method and composition are effective for prevention, treating or ameliorating cardiovascular diseases such as myocardial infarction, stroke and multiple arteriosclerosis by the reduction or prevention of high levels of plasma homocysteine, one of the major causes for such diseases. Methods and compositions are disclosed.

folic acid/infarction

Application of phytosterols (and their isomers), folic acid, cyanocobalamin and pyridoxin in dietetic (alimentary) fibers

Method and pharmaceutical composition for reducing serum homocysteine concentration

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