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Aryl hydrocarbon receptor nuclear translocator protein 2 (ARNT2), a member of the basic helix-loop-helix superfamily of transcription factors, may serve a vital role in neuronal survival and cell proliferation via formation of heterodimers with hypoxia-inducible factor-1α. Previous studies indicated
The emissions of particle-phase polycyclic aromatic hydrocarbons (PAHs) were evaluated in the exhaust of four (two EURO-0 and two EURO-1) four-stroke engine, in-use scooters with displacement of 150 cc, which were not equipped with catalytic converters. Non-catalysed motorcycles still represent a
Exposure to air pollutants is known to have adverse effects on human health; however, little is known about the association between hydrocarbons in air and an ischemic stroke (IS) event. We investigated whether long-term exposure to airborne hydrocarbons, including volatile organic compounds,
BACKGROUND
Aryl hydrocarbon receptor (AhR) is a transcription factor that belongs to the basic helix-loop-helix PAS (Per-Arnt-Sim homology domain) family known to mediate the toxic and carcinogenic effects of xenobiotics. Interestingly, AhR is widely expressed in the central nervous system, but its
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor activated by environmental agonists and dietary tryptophan metabolites for the immune response and cell cycle regulation. Emerging evidence suggests that AHR activation after acute stroke may play a role in Thus, this study was undertaken to determine the size distribution, concentration, species, and carcinogenic potency of particulate matter and particle-bound polycyclic aromatic hydrocarbons (PAHs) emitted from 4-st/mc at various speeds (idle, 15 km/h, 30 km/h). Approximately 80% of the particles
The aromatic hydrocarbons benzene, toluene and C2-benzenes (ethyl benzene and m,p,o-xylene) (BTEX) were measured during a 2-month monitoring campaign in 2007 in the Arctic town of Longyearbyen (Spitsbergen, Svalbard). Reflecting the remoteness of the location, very low mixing ratios were observed
Two-stroke petrol engines find wide applications in the areas like chain saws, weed cutters, and power sprayers because of their compactness and higher power to weight ratio. In the present study, the feasibility of using vegetable-based lubricant instead of ordinary mineral 2 T oil is investigated.
This study aimed to determine whether the coding (A4889G) and noncoding region (T6235C) polymorphisms of the gene coding for cytochrome P4501A1 (CYP1A1), a xenobiotic-metabolizing enzyme responsible for the metabolism of carcinogenic polycyclic aromatic hydrocarbons, are involved in the pathogenesis
Proper regulation of the aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor, is required for normal vertebrate cardiovascular development. AHR hyperactivation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during zebrafish (Danio rerio) development results in altered heart
BACKGROUND
Polycyclic aromatic hydrocarbons (PAHs) are potent atmospheric pollutants produced by incomplete combustion of organic materials. Pre-clinical and occupational studies have reported a positive association of PAHs with oxidative stress, inflammation and subsequent development of
Variability refers to real differences in emissions among multiple emission sources at any given time or over time for any individual emission source. Variability in emissions can be attributed to variation in fuel or feedstock composition, ambient temperature, design, maintenance, or operation.
Commercial fishers are exposed to unburned hydrocarbon vapors and combustion products present in the emissions from their boat engines. The objective of this study was to measure personal exposure to benzene as a marker of fuel exposure, and to predict exposure levels across categories of carbureted
Small utility engines represent an important contribution to the emissions inventory and have been subjected to increasingly stringent regulations in recent years. For this project, a Tanaka two-stroke engine was tested in its original condition and with a modified fuel/oil injection system. The
Emission characteristics from a four-stroke motorcycle engine using 10% (v/v) ethanol-gasoline blended fuel (E10) were investigated at different driving modes on the chassis dynamometers. The results indicate that CO and HC emissions in the engine exhaust are lower with the operation of E10 as