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11 resultaten
High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesity.
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BACKGROUND
Obesity has been associated with a more severe disease course in inflammatory bowel disease (IBD) and epidemiological data identified dietary fats but not obesity as risk factors for the development of IBD. Crohn's disease is one of the two major IBD phenotypes and mostly affects the
Granulomatous colitis and ileitis complicating jejunoileal bypass.
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There are many complications of a jejunoileal bypass for obesity. I report what is, to my knowledge, a previously unrecognized complication--granulomatous colitis and ileitis. Caution is urged in recommending this procedure for the treatment of obesity.
Jejunoileal bypass for morbid obesity. Report of a series with long-term results.
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Of 72 patients who underwent jejunoileal bypass because of morbid obesity, 69 could be evaluated with special reference to long-term (median 11 years) results. One of the other three had fatal anastomotic leakage, one underwent resection and reversal of shunt because of postoperative gangrene in the
Maternal High-fat Diet Accelerates Development of Crohn's Disease-like Ileitis in TNFΔARE/WT Offspring.
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BACKGROUND
Maternal high-fat diet (HFD) and obesity increases the risk of the offspring to develop inflammatory processes in various organs including the gut. We hypothesized that maternal diet-induced obesity programs the fetal gut towards inflammation in a mouse model of genetically-driven Crohn's
Pathogenesis of cholesterol gallstones.
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The factors leading to cholesterol cholelithiasis are probably multiple. Although the secretion of bile supersaturated with cholesterol seems to be a common feature among all patients who form cholesterol stones, a variety of pathophysiologic events can produce an increase in lithogenicity. Dietary
Current status of the continent ileostomy.
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The continent ileostomy has substantial advantages over the standard ileostomy in that it provides a socially acceptable, odourless, appliance-free stoma. The author presents the experience at the Toronto General Hospital from 1977 to 1984 with this procedure which was performed on 123 patients, in
[Conservative treatment for omental infarction].
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The omental infarction is a pathology that occurs more and more in children due to the increased use of imaging studies and the increment in overweigth and obesity. Clinical presentation is characterized by abdominal pain and can be confused with appendicitis, ileitis, adenitis, among other
Can ultrasound be used as the primary imaging in children with suspected Crohn disease?
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BACKGROUND
There is growing literature on the use of ultrasound (US) for evaluation of Crohn disease in adults, but few studies have been conducted on children. Several studies demonstrated high accuracy of US in the diagnosis of Crohn disease. Using US as the primary screening imaging modality for
Diminished expression of apical sodium-dependent bile acid transporter in gallstone disease is independent of ileal inflammation.
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BACKGROUND
Non-obese gallstone patients exhibit a diminished expression of apical sodium-dependent bile acid transporter (ASBT) in terminal ileum. Crohn's ileitis demonstrates a significant downregulation of this transporter.
OBJECTIVE
To test whether subclinical ileal inflammation contributes to
Does laparoscopic intracorporeal ileocolic anastomosis decreases surgical site infection rate? A propensity score-matched cohort study.
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OBJECTIVE
Foreshortened mesentery or thick abdominal wall constitutes a rationale for laparoscopic intracorporeal ileocolic anastomoses (ICA). The aim of this study was to compare intracorporeal to extracorporeal ICA in terms of surgical site infections in patients with Crohn's ileitis and
Role of gamma delta T cells in inflammatory bowel disease.
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gammadelta T cells have previously been shown to play a protective role in various animal models of chronic inflammation (e.g., experimental autoimmune encephalomyelitis, collagen-induced arthritis, and non-obese diabetes). This immunoregulatory potential is exerted by synthesizing various
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