A novel compound showing anti-tumor properties was synthesized by reacting Cp.sub.2TiCl.sub.2 with maltol (3-hydroxy-2-methyl-4-pyrone) and a pH of 5.4, leading to a complete replacement of Cp and chloride ligands affording, Ti(maltolato).sub.2(OH).sub.2. The further crystallization of Ti(maltolato).sub.2(OH).sub.2 at pH of 8.4 leads to the formation of the novel anti-tumor compound [Ti.sub.4(maltolato).sub.8(.mu.-O.sub.4)].

University of Puerto Rico

Titanium-maltol compound and method of synthesizing the same

An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.

Reddy; Varattur Dayal

Research Foundation of The City University of New York

Organometallic anti-cancer complexes

Disclosed is an agent which has a destructive effect on malignant tumors and contains alpha-ketoglutaric acid, N-acetyl-seleno-L-methionine, N-acetyl-L-methionine, and a compound that is capable of forming azomethine and is selected among the group 5-hydroxymethylfurfural, dehydroascorbic acid, maltol, and vanillin as an active substance, 5-hydroxymethylfurfural being preferred. The inventive agent can be used in the form of an infusion, in an oral or rectal form of administration, or as an irrigation in cancer therapy.

maltol/kanker

Titanium-maltol compound and method of synthesizing the same

Organometallic anti-cancer complexes

Agent having a destructive effect on malignant tumors and method for the production thereof

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