meningeal carcinomatosis/hoofdpijn

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Headache in a young woman: leptomeningeal metastasis as the first presentation of underlying breast malignancy.

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A 37-year-old woman presented with a 2-week history of persistent headache in an occipitotemporal distribution. The patient had experienced prior headaches and migraines, but this presentation was characterised by its intensity and duration. There was associated dizziness and blurring of vision in

[Carcinomatous meningitis presenting with isolated headache].

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BACKGROUND Carcinomatous meningitis reveals a solid cancer in 10 percent of cases. METHODS Our patient developed isolated headache which progressively worsened. Cranial Computerized Tomography (CT) was normal. Brain MRI showed multiples areas of contrast enhancements meningeal tissue associated with

Leptomeningeal metastasis from occult signet-ring cell colon adenocarcinoma presenting with isolated headache.

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We report a patient with a rare primary signet-ring cell carcinoma of the transverse colon with secondary leptomeningeal carcinomatosis. The only presenting and persistent symptom was worsening headache for 6 weeks until death. There were no other neurological, constitutional, or gastrointestinal

Refractory headache in a patient with breast cancer and carcinomatous meningitis unresponsive to analgesics: case report.

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A 44-year old female presented with locally advanced breast cancer that had been treated with neoadjuvant chemotherapy followed by modified radical mastectomy and thereafter three cycles of paclitaxel. She presented with severe refractory headache that was unresponsive to oral analgesics including

Rizatriptan is effective for headache in a patient with meningeal carcinomatosis.

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Leptomeningeal carcinomatosis: an unusual cause of headache in bronchial carcinoma.

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Leptomeningeal metastasis presenting with blurry vision, nausea and headache

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Treatment of leptomeningeal carcinomatosis with continuous intraventricular infusion of recombinant interleukin-2.

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A 42-year-old man developed leptomeningeal carcinomatosis 6 years after treatment of a malignant melanoma. He was treated with two courses of recombinant interleukin-2, administered as a continuous intraventricular infusion (6 X 10E5 U/24 h) during 5 days. During the first day of the first course he

[Meningeal carcinomatosis as the first manifestation of gastric adenocarcinoma].

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Gastric adenocarcinoma is rarely observed in patients under the age of 40. Meningeal carcinomatosis as a first manifestation of disease is absolutely unique. If meningeal involvement occurs it is usually secondary event in previously diagnosed tumor. The prognosis is very unfavorable associated with

Intrathecal cytostatic therapy of meningeal carcinomatosis. Autoradiographic investigations of the CSF cells.

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Autoradiographic investigations with 3H-thymidine were performed on cerebrospinal fluid (CSF) cells from a case of meningeal carcinomatosis following carcinoma of the breast. The cells were found to be anaplastic histologically. Within a period of 12 days 3 X 25 mg methotrexate were injected into

Prolonged response of meningeal carcinomatosis from non-small cell lung cancer to salvage intrathecal etoposide subsequent to failure of first-line methotrexate: a case report and literature review.

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BACKGROUND As the incidence of meningeal carcinomatosis (MC) in non-small cell lung cancer (NSCLC) patients has been increasing, MC has recently become an important clinical problem in the management of NSCLC. However, development of new treatments is lacking and a standard treatment guideline is

Leptomeningeal metastasis from prostate cancer.

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OBJECTIVE Metastatic prostate carcinoma commonly involves bones and extrapelvic lymph nodes, with occasional visceral deposits. Central nervous system involvement is unusual and particularly the occurrence of leptomeningeal metastasis (LM) is extremely rare, with few cases described in the medical

Intra-CSF topotecan in treatment of breast cancer patients with leptomeningeal metastases

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Background: There are few treatment options for patients with leptomeningeal metastases (LM). Methods: We report a case series of patients with breast cancer and LM treated

Multiple cerebral and leptomeningeal metastases from ovarian carcinoma: unusual early presentation.

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Although virtually any systemic malignancy is capable of metastasizing to the brain, ovarian carcinoma, one of the more common female genital malignancies, is one of the rarer forms of brain metastases. In general, the outcome for ovarian carcinoma with brain metastases is extremely poor as most of

[A case of lumboperitoneal shunt as an effective palliative tool in a patient with leptomeningeal metastasis].

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A 64 year-old woman with a diagnosis of lung adenocarcinoma was admitted to our neurosurgical division in February, 2007, suffering from severe headache and dizziness. Systemic chemotherapy had been repeated for multiple metastases to the bone and cerebral cortex since 7 months before. Reexamination

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