mydriasis/hyoscine

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Transdermal hyoscine induced unilateral mydriasis.

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The authors present a case of unilateral mydriasis in a teenager prescribed transdermal hyoscine hydrobromide (scopolamine) for chemotherapy induced nausea and vomiting. The authors discuss the ocular side-effects associated with this particular drug and delivery system and the potential use of

Accidental Unilateral Mydriasis from Hyoscine Patch in a Care Provider.

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The hyoscine patch is effective and is frequently used in motion sickness treatment. Not uncommonly, it is used to control excessive respiratory secretions in palliative patients. Patients, healthcare workers, and caregivers who administer these may experience a benign, although worrying, mydriasis

Ocular effects of hyoscine in double dose transdermal administration and its reversal by low dose pyridostigmine.

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The potential of low dose (30 mg t.i.d) pyridostigmine to reduce the ocular side effects of double dose transdermal controlled release hyoscine was evaluated by the study of near visual acuity, accommodation amplitude and pupil diameter in a placebo controlled, double masked study. We studied 47

The effects of 0.025% hyoscine hydrobromide eyedrops on visual function in man.

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Instillation of three drops of 0.025% hyoscine hydrobromide into one eye at 5 min intervals caused a mydriasis and cycloplegia of rapid onset and of 4-6 days' duration; this was similar to the previously reported actions of concentrations of up to 0.5%. After refraction for the working distance of

Three cases of substitution errors leading to hyoscine hydrobromide overdose.

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We report three patients with anticholinergic poisoning caused by the substitution of hyoscine hydrobromide for hyoscine butylbromide in preparations compounded by two different pharmacists. The patients took the preparations for gastrointes tinal discomfort and presented with altered mental status

Temporary diplopia upon hyoscine-N-butyl bromide administration: case report.

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Hyoscine-N-butyl bromide is a widely used antispasmodic belonging to the belladonna alkaloid class of semisynthetic quaternary ammonium compounds. These compounds exert a spasmolytic action on the smooth muscles of the bile-gastrointestinal tract, genitourinary tract, salivary glands (xerostomia),

Hyoscine skin patches for drooling dilate pupils and impair accommodation: spectacle correction for photophobia and blurred vision may be warranted.

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Hyoscine skin patches diminish salivation by their anticholinergic action. The aim of reporting this case series is to present the ophthalmic side effects in children, and to highlight the precautions to take. Five children (two males, three females; age range 8-18y) with quadraplegic cerebral palsy

Transdermal hyoscine (Scopolamine). A preliminary review of its pharmacodynamic properties and therapeutic efficacy.

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Hyoscine (scopolamine) is a competitive inhibitor of the muscarinic receptors of acetylcholine and it has been shown to be one of the most effective agents for preventing motion sickness. However, a relatively high incidence of side effects and a short duration of action has restricted the

Efficacy of tropicamide, homatropine, cyclopentolate, atropine and hyoscine as mydriatics in Angora goats.

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OBJECTIVE To document the efficacy of five commercially available mydriatics for their potential for diagnostic and therapeutic use in Angora goats. METHODS Over 8 weeks, the mydriatic effects of 1% tropicamide, 2% homatropine, 1% cyclopentolate, 1% atropine and 0.25% hyoscine were evaluated. Given

Visual side-effects from transdermal scopolamine (hyoscine).

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Transdermal scopolamine may be used to reduce drooling in children with disabilities. Side-effects include dilated pupils and a reduction in the near point of accommodation (the closest point at which clear vision is possible). Two male children with epilepsy, one with spinal dysraphism (aged 7y

[Acute monosymptomatic anisocoria after removing a scopolamine patch from a patient].

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Acute anisocoria requires timely examination to rule out intracranial pathology. This case report describes a 34-year-old nurse who experienced blurred vision and unilateral mydriasis. She had no other complaints, and neurological examinations were normal. Shortly before, she had removed a

[Angel trumpets: case report of drug-induced psychosis caused by Brugmansia insigniis].

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A case of a psychosis induced by ingestion of blossoms of the solanum Brugmansia insigniis is presented. This plant is used by young persons as a hallucinogenic drug. The psychopathology of this kind of intoxication has not been documented in the literature up to now. It is characterized by

Formation of scopolamine from N-butyl-scopolammonium bromide in cigarettes.

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Scopolamine (hyoscine) is a naturally occurring alkaloid found in solonacea, the so-called "night shade" plants. Therapeutic applications of scopolamine are in ophthalmology to cause mydriasis and for the prevention of motion sickness, among others. It is known to induce hallucinogenic effects at a

Collective poisoning with hallucinogenous herbal tea.

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An incident wherein more than 30 people were poisoned with a herbal infusion during a meditation session is described. The clinical features observed were hallucinations, aggression, agitation, amnesia, mydriasis, dry skin, tachycardia, hyperthermia, hypotension, collapse, coma and respiratory

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