5 resultaten
OBJECTIVE
Assessment of the value of determination of antineutrophil cytoplasmic antibodies (ANCA) and its specificities for classification of patients with biopsy-proven necrotizing arteritis.
METHODS
The serum samples of 28 consecutive patients with biopsy-proven vasculitis involving medium-
We present a case of classical polyarteritis nodosa (PN) overlapping thrombotic thrombocytopenic purpura (TTP). A 70-year-old woman was transferred to our hospital because of general fatigue and fever. On admission, laboratory findings revealed leukocytosis, normochromic normocytic anemia and renal
OBJECTIVE
To study the clinical characteristics and epidemiology of the combination of primary systemic vasculitis (PSV) and severe alpha-1 antitrypsin (α1-AT) deficiency.
METHODS
Patients with PSV [granulomatosis with polyangiitis (GPA) (Wegener's), microscopic polyangiitis, eosinophilic
Panarteritis nodosa, Wegener's granulomatosis and idiopathic necrotizing glomerulonephritis, regarded by some as a vasculitis restricted to the glomerulus, are those forms of primary vasculitis most often encountered in renal biopsy. The histopathologic differential diagnosis can be difficult and
Antineutrophil cytoplasmic antibodies (ANCA) have been described as sensitive and specific markers for active Wegener's granulomatosis (WG). ANCA in WG produce a characteristic cytoplasmic staining pattern of neutrophils (c-ANCA) and are directed against proteinase 3 (Pr3), a serine protease from