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Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A.

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Polysaccharide A (PSA), an immunogenic capsular component of non-toxigenic Bacteroides fragilis (NTBF) strain NCTC 9343, is reported to promote mucosal immune development and suppress colitis. Contrastingly, enterotoxigenic Bacteroides fragilis (ETBF) is highly associated with inflammatory bowel

Anti-colon-cancer effects of polysaccharides: A mini-review of the mechanisms.

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Polysaccharides are an important class of functional phytochemicals, and various studies have demonstrated the beneficial pharmacological effects of polysaccharides, including against colorectal cancer and colitis. Numerous studies have shown that natural polysaccharides display anti-colon cancer

Licorice and cancer.

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Licorice root is one of the oldest and most frequently employed botanicals in Chinese medicine. In the United States, licorice products are most often used as flavoring and sweetening agents in food products. Constituents of licorice include triterpenoids, such as glycyrrhizin and its aglycone

Astragalus polysaccharide, a component of traditional Chinese medicine, inhibits muscle cell atrophy (cachexia) in an in vivo and in vitro rat model of chronic renal failure by activating the ubiquitin-proteasome pathway.

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The present study aimed to determine the effect of Astragalus polysaccharide (APS) in an in vivo and in vitro rat model of muscle atrophy (cachexia) caused by chronic renal failure (CRF), along with the potential corresponding roles of atroglin-1 and the ubiquitin-proteasome pathway. A rat model of

Maca polysaccharides: A review of compositions, isolation, therapeutics and prospects.

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Maca polysaccharides, some of the major bioactive substances in Lepidium meyenii (Walp.) (Maca), have various biological properties, including anti-oxidant, anti-fatigue, anti-tumor, and immunomodulatory effects, as well as hepatoprotective activity and regulation function. Although many

Grifola frondosa polysaccharide: a review of antitumor and other biological activity studies in China.

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Grifola frondosa, a species of Basidiomycotina, is an edible medicinal mushroom with a large fruiting body characterized by overlapping caps. The β-glucan is the major biologically active component in G. frondosa polysaccharide (GFP) or D-fraction, which has been studied extensively for nearly 30

Immunomodulatory dietary polysaccharides: a systematic review of the literature.

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BACKGROUND A large body of literature suggests that certain polysaccharides affect immune system function. Much of this literature, however, consists of in vitro studies or studies in which polysaccharides were injected. Their immunologic effects following oral administration is less clear. The

Selenylated plant polysaccharides: A survey of their chemical and pharmacological properties.

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Polysaccharides from plants and fungi are considered nowadays as powerful pharmacological tools with a great therapeutic potential. In the meantime, efforts have been addressed to set up effective chemical modifications of naturally occurring polysaccharides to improve their biological effects as

Effects of aloe polysaccharide, a polysaccharide extracted from Aloe vera, on TNF‑α‑induced HaCaT cell proliferation and the underlying mechanism in psoriasis.

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Aloe vera is a traditional wound‑healing medicine used for the treatment of skin disorders. Aloe polysaccharide (APS) is the main macromolecule of Aloe vera, which contributes to its function. Psoriasis is an immune‑mediated chronic inflammatory disease, which affects 2‑3% of the general population.

The immunostimulating role of lichen polysaccharides: a review.

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The immune system has capacity to suppress the development or progression of various malignancies including cancer. Research on the immunomodulating properties of polysaccharides obtained from plants, microorganisms, marine organisms, and fungi is growing rapidly. Among the various potential

Composition, isolation, purification and biological activities of Sargassum fusiforme polysaccharides: A review.

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Sargassum fusiforme polysaccharides, acidic water-soluble polysaccharides extract from Sargassum fusiforme, are mainly composed of alginic acid, fucoidan and laminaran. Alginic acid is carboxyl-containing polysaccharide formed by joining β-D-mannuronic acid and α-L-guluronic acid through

Extraction, characterization, utilization as wound dressing and drug delivery of Bletilla striata polysaccharide: A review.

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This review provides updated information on a kind of active polysaccharides extracting from Chinese traditional herb Bletilla striata. Preliminary investigations have listed several isolation approaches of extracting Bletilla striata polysaccharide (BSP) and the characterization result showed that

Extraction methods, chemical characterizations and biological activities of mushroom polysaccharides: A mini-review

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Edible mushrooms are an important constituents of our daily diet due to their rich nutrition and beneficial properties for human health. Polysaccharides, the main component of edible mushrooms, attracted more and more attention because of their complex structure and diverse biological activities.

Anti-Diabetic Effect of Portulaca oleracea L. Polysaccharideandits Mechanism in Diabetic Rats.

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Diabetes mellitus (DM) is a metabolic syndrome caused by multiple genetic and environmental factors. Traditional Chinese medicine preparations have shown a comprehensive and function-regulating characteristic. Purslane (Portulaca oleracea L.) is an annual succulent herb. Currently, there have been

Antitumor activity of Se-containing tea polysaccharides against sarcoma 180 and comparison with regular tea polysaccharides and Se-yeast.

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Selenium (Se)-containing polysaccharide, a Se-conjugate macromolecule, generally exhibited higher antitumor activity than its regular polysaccharide. Previously, we extracted Se-containing tea polysaccharides (Se-TPS) from Se-enriched tea, and explored its structure and antioxidant activity. In this

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