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[Microeconomic evaluation of a mass preventive immunisation campaign against meningococcal meningitis and yellow fever in Senegal in 1997].

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Large epidemics of group A meningococcal meningitis occurred in 1995 and 1996 in several countries of the Sub-Saharan Africa zone known as the "meningitis belt", and more particularly in West Africa. Most of these countries affected by the epidemics met difficulties to set up the strategy

[The secretory and systemic humoral immune response to polysaccharide A in patients with rheumatism].

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The level of sIgA saliva antibodies and Ig(M + G + A) serum antibodies to group polysaccharide A of streptococcus was studied in healthy donors and patients with streptococcal angina and rheumatic fever. It was shown that an elevated level of secretory and serum antibodies to polysaccharide A was

IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model.

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Vaccination against Salmonella Typhi using the Vi capsular polysaccharide, a T-cell independent antigen, can protect from the development of typhoid fever. This implies that antibodies to Vi alone can protect in the absence of a T cell-mediated immune response; however, protective Vi

[Group A streptococcal polysaccharide--an inhibitor of the functional activity of T-suppressors induced by Con A in a culture of mononuclear cells of human peripheral blood].

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It was found that group A streptococcal polysaccharide (A-PS) had no mitogenic effect on the intact human blood mononuclear cells' culture (MNC) and on its proliferation stimulated with ConA. Using a double staining technique for simultaneously determining cell surface phenotype and degree of cell

[Autoantibodies to the common antigenic determinant of group A streptococcal polysaccharide and epithelial cells of mammalian thymus and skin].

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A cross-reactive (CR) antigenic determinant in the polysaccharide of group A streptococus and the mammalian thymus and skin was studied. The CR antigen was found in adult humans and human embryos irrespective of the blood group, as well as in the tissues of all the animal species studied, including

Adverse events after polysaccharide meningococcal A&C vaccine.

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The incidence of adverse events due to meningococcal polysaccharide A&C vaccine was studied in 312 subjects 18 months to 20 y of age who were part of a mass vaccination program. Fever > 38 degrees C occurred in 5.1% (95% CI: 3.1-8.4%). Injection site pain was reported in 78.8% (95% CI: 74.3-83.4%),

Assay for antibodies to group C and G streptococcal carbohydrate by enzyme-linked immunosorbent assay.

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An enzyme-linked immunosorbent technique was established for the assay of serum antibodies to the group C and G streptococcal group-specific carbohydrates. The antigens consisted of formamide-extracted purified polysaccharides conjugated to poly-L-lysine. By use of hyperimmune rabbit antisera to the

[Streptococcal group A carriage: new data on the characteristics of the biology of the causative agent and of the immune response of the host].

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Carriership of group A streptococcus (A-STR) was registered with significantly greater frequency among children of preschool and early school age (29.8%) than among adults (4.0%). Cultures of A-STR isolated from carriers were characterized by their low capacity for secreting erythrogenic toxin of

Vi capsular polysaccharide: Synthesis, virulence, and application.

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Vi capsular polysaccharide, a linear homopolymer of α-1,4-linked N-acetylgalactosaminuronate, is characteristically produced by Salmonella enterica serovar Typhi. The Vi capsule covers the surface of the producing bacteria and serves as an virulence factor via inhibition of complement-mediated

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