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serum sickness/hoofdpijn

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Delayed serum sickness-like transfusion reactions in a multiply transfused patient.

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The clinical features and progress of a patient with a fatal myeloproliferative disease are reported. Her care required frequent transfusions of red cell products and components. These transfusions were followed, after varying intervals, by fever, arthralgia, myalgia, headache and pericarditis.

A possible case of serum sickness after ocrelizumab infusion

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A 41-year-old female diagnosed with multiple sclerosis began ocrelizumab treatment. She received her first treatment course without significant complication. After receiving the first maintenance dose 6 months later, she developed weakness, myalgias, gastrointestinal symptoms, headache, and

Serum sickness-like syndrome due to mosquito bite.

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Local inflammatory reactions at the site of a mosquito bite are frequent. Immediate systemic reactions have occasionally been reported. The first case of a patient with relapsing episodes of a serum sickness-like syndrome following mosquito bites is reported herein. A 62-year-old patient came to the

Antivenin-related serum sickness.

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Serum sickness is a type III hypersensitivity reaction that occurs due to the deposition of excessive circulating immune complexes in patients treated with foreign proteins or haptens. Serum sickness induced by antivenin for snakebites has been frequently reported in the USA, but not in Taiwan. This
We have prospectively evaluated the clinical and immunological features of serum sickness in 35 patients treated for bone marrow failure with anti-thymocyte globulin (ATG 15 mg/kg/day) and methylprednisolone (1 to 1.5 mg/kg/day). Twenty-one patients were treated for 10 days and 14 were treated for

Survey on the use of adalimumab as maintenance therapy in Crohn's disease in England and Ireland.

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BACKGROUND Adalimumab is effective in inducing and maintaining response/remission in patients with Crohn's disease either naive to biological therapies or after secondary failure of infliximab. OBJECTIVE To present the first 'real-life' survey data from England and Ireland on the use of

Surveillance of adverse effects during a vaccination campaign against meningitis C.

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OBJECTIVE To describe adverse events occurring after mass vaccination with conjugate and nonconjugate vaccines and to assess the incidence of serious adverse effects. METHODS A mass immunisation campaign against meningococcal C disease was conducted in two French administrative areas, Landes and

Comparison of the efficacy and tolerability of ivabradine and ranolazine in patients of chronic stable angina pectoris.

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BACKGROUND To compare the efficacy and tolerability of Ivabradine (IVA) and Ranolazine (RAN) in chronic angina patients. METHODS This was a follow-on, open-label trial conducted in a tertiary care hospital of Uttarakhand. Thirty patients each taking IVA 5 mg twice daily or RAN 500 mg twice daily

Bupropion sustained release. A therapeutic review of Zyban.

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BACKGROUND Originally developed as an antidepressant, bupropion hydrochloride is a selective re-uptake inhibitor of dopamine and noradrenalin which was found to reduce nicotine withdrawal symptoms and the urge to smoke. Bupropion came onto the Australian market in November 2000 as a 150 mg sustained

Treatment of aplastic anemia with antithymocyte globulin, high-dose corticosteroids, and androgens.

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A total of 46 patients with aplastic anemia (34 severe; 12 moderate) were treated with antihuman thymocyte globulin (ATG), high-dose methylprednisolone, and oxymetholone. Early symptoms of ATG toxicity included fever, rash, and bronchospasm. Signs of serum sickness also developed in 23 patients.

Evaluation of long-term safety of the anti-IgE antibody, omalizumab, in children with allergic asthma.

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OBJECTIVE To evaluate the long-term effects of the anti-IgE antibody omalizumab in children with asthma. METHODS This was a 28-week, double-blind, randomized, placebo-controlled trial with a 24-week open-label extension. In the core trial 225 children (ages 6 to 12 years) with moderate-to-severe
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