ventricular fibrillation/albumine

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Effect of albumin on the electrophysiologic stability of isolated perfused rabbit hearts.

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The electrophysiologic stability of isolated perfused rabbit hearts was evaluated over a period of 5 h. Hearts perfused with protein-free buffer deteriorated over time, with significant shortening of the ventricular effective refractory period (ERP) and development of ventricular fibrillation. When

Serum albumin level and long-term outcome in acute heart failure.

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Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of long-term mortality in patients admitted for

Ischaemia-modified albumin predicts the outcome of cardiopulmonary resuscitation: An experimental study.

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BACKGROUND Ischaemia-modified albumin (IMA) has recently been shown to be an early and sensitive marker of ischaemia. It is generally accepted that cardiac arrest causes the most severe form of global ischaemia. The aim of the present study was to identify whether IMA is an independent predictor of

Relationship between the extent of the hypoperfused zone of the myocardium and the occurrence of ventricular fibrillation.

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Ventricular fibrillation and subsequent death frequently occur so soon after coronary artery occlusion that infarct size cannot be determined; thus the systematic study of their relationship is impossible. Recently, however, a technique has been developed that permits the assessment, in vivo, of the

Effect of palmitic acid and fatty acid binding protein on ventricular fibrillation threshold in the perfused rat heart.

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The effects of increased free fatty acid (FFA) levels on ventricular arrhythmias remain controversial. Using ventricular fibrillation threshold (VFT), we examined the relationship between FFA levels and ventricular arrhythmias. Isolated rat hearts were perfused with palmitate bound to either albumin

Serum albumin level and hospital mortality in acute non-ischemic heart failure.

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OBJECTIVE Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of hospital mortality in patients admitted for acute

Effect of exogenous fatty acids on reperfusion arrhythmias in isolated working perfused hearts.

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Exogenous fatty acids may promote arrhythmias during ischemia and reperfusion, perhaps by increasing myocardial concentrations of long-chain acylcarnitines. We therefore studied the effects of high concentrations of fatty acids on reperfusion arrhythmias and acylcarnitine accumulation in isolated

Antiarrhythmic effects of ceruloplasmin during reperfusion in the ischemic isolated rat heart.

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The ability of ceruloplasmin, an important serum antioxidant, to reduce the vulnerability of the isolated rat heart to reperfusion arrhythmias has been investigated. Bovine plasma ceruloplasmin was purified by chromatography on aminoethyl-agarose. Isolated rat hearts were submitted to 15 min of

Aggregate anaphylaxis and carboxypeptidase N.

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Bradykinin (BK) is widely believed to play a role in the pathogenesis of anaphylaxis. To help clarify any such roles, we examined for effects of inhibitors of kininase II (angiotensin converting enzyme, ACE) and "kininase I" (carboxypeptidase N, CPN), on the early course of egg albumin-induced

Myocardial effects and pharmacokinetics of digoxin and ouabain in protein-deficient guinea pigs.

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Myocardial effects and pharmacokinetics of digoxin and ouabain were studied in male albino guinea pigs fed ad libitum either a 21% (control) or a 5% (low) protein diet for 4 weeks. Dietary protein deficiency was associated with a decrease in body weight gain, ventricular weight, total plasma

Hematologic and chemical changes observed during and after cardiac arrest in a canine model--a pilot study.

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OBJECTIVE To evaluate the effect of cardiac arrest and cardiopulmonary resuscitation (CPR) on blood chemistry in a canine model. METHODS Evaluative canine animal study. METHODS Animal laboratory accredited by the Association for Assessment and Accreditation of Laboratory Animals. METHODS Twenty-six

[New guidelines for basic and advanced resuscitation of adults and children].

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We present the latest changes in the guidelines for resuscitation from the International Liaison Committee on Resuscitation (ILCOR). Defibrillation performed by non-medical personnel is more strongly endorsed than before. In unintubated patients the ventilation-to-compression ratio should always be

[Studies on the mechanism of arrhythmogenic action of free fatty acid].

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It was reported that free fatty acid (FFA) is one of the important factors which cause ventricular arrhythmias during acute myocardial infarction. However the mechanism is still unclear. Measuring ventricular fibrillation threshold (VFT), the mechanism of FFA was investigated in perfused rat heart.

[Physiopathology of accidental drowning].

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The first phase of accidental drowning begins with asphyxia, due to either laryngospasm (10-15 percent of cases) or water aspiration. The second phase is characterized by water and electrolyte changes in the blood. The physiopathological modifications caused by drowning in fresh water differ from

Volume expansion during cardiopulmonary resuscitation reduces cerebral no-reflow.

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Resuscitation of the brain after cardiac arrest requires homogeneous blood recirculation which, however, may be impaired by low reperfusion pressure, intravascular coagulation, increased blood viscosity and endothelial cell swelling. Intravascular volume expansion induced by intravenous infusion of

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