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4 resultater
Influence of recanalization on uric acid patterns in acute ischemic stroke.
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BACKGROUND
Most epidemiological studies have reported a significant association between elevated serum levels of uric acid (UA) and increased cardiovascular disease. On the other hand, UA is the most abundant antioxidant in the human body. We hypothesized that UA levels would change noticeably in
Uric acid therapy for vasculoprotection in acute ischemic stroke.
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Uric acid (UA) is a product of the catabolism of purine nucleotides, the principal constituents of DNA, RNA, and cellular energy stores, such as adenosine triphosphate. The main properties of UA include scavenging of hydroxyl radicals, superoxide anion, hydrogen peroxide, and peroxynitrite that make
Oxidative damage in ischemic stroke revealed using multiple biomarkers.
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OBJECTIVE
We investigated changes in oxidative damage after ischemic stroke using multiple biomarkers.
METHODS
Serial blood and urine samples of ischemic stroke subjects and age-matched control subjects were assayed for F₂-isoprostanes, hydroxyeicosatetraenoic acid products, F₄-neuroprostanes,
Uric Acid Therapy Improves Clinical Outcome in Women With Acute Ischemic Stroke.
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OBJECTIVE
It is unknown whether women and men with acute ischemic stroke respond similar to an antioxidant regimen administered in combination with thrombolysis. Here, we investigated the independent effect of sex on the response to uric acid (UA) therapy in patients with acute stroke treated with
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