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arsenic/hemorrhage

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Does dietary arsenic and mercury affect cutaneous bleeding time and blood lipids in humans?

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Fish species may contain considerable amounts of trace elements, such as selenium (Se), arsenic (As), and mercury (Hg). The present study investigated the relationships between dietary intake of these elements and cutaneous bleeding time and blood lipids in 32 healthy volunteers. For 6 wk, one group
OBJECTIVE The arsenic trioxide (ATO) plus all-trans retinoic acid (ATRA) therapy has demonstrated a tremendous success in the first-line treatment of acute promyelocytic leukemia (APL). Actually, early death (ED) is currently thought as a major challenge in APL. ATO has been reported to inhibit
OBJECTIVE The case of a patient who developed acute renal failure, gastrointestinal bleeding, and cardiac arrhythmia after receiving arsenic trioxide for the treatment of acute promyelocytic leukemia (APL) is described. CONCLUSIONS An 84-year-old Caucasian woman with a history of osteoarthritis

Hemorrhagic encephalopathy during arsenic therapy for asthma.

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Use of Novoseven for arsenic trioxide-induced bleeding in PML.

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So-called bleeding ulcer proving to result from arsenic poisoning.

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Massive variceal hemorrhage secondary to presinusoidal portal hypertension due to arsenic poisoning.

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Inorganic arsenic toxicosis in cattle.

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In 4 occurrences of arsenic poisoning in cattle, the principal clinical sign was acute hemorrhagic diarrhea attributable to hemorrhagic gastroenteritis. Arsenic concentrations in the liver, kidney and rumen contents varied. In one occurrence, arsenic in the hair of affected survivors was assayed at
Mortality and morbidity of vascular diseases, including stroke, are known to be associated with chronic exposure to inorganic arsenic through drinking water. A tap-water supply system was implemented in the early 1960s in the blackfoot disease (BFD) endemic areas of Taiwan. The objective of this

Arsenic and metaldehyde toxicosis in a beef herd.

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Over a 12-day period, 13 animals in a herd of 110 beef cattle developed ataxia with profound muscle fasciculations progressing to recumbency. Twelve animals (5 adults and 7 calves from 8-10 months of age) died, and 1 cow was euthanized. Hemorrhagic diarrhea occurred in some, but not all, animals.
Hepatic angiosarcoma is an infrequent neoplasm representing 1-3% of all the primary liver cancers. One fourth of the cases have demonstrated a relation with chemical carcinogens with the most frequent being thorium dioxide (thorotrast) and vinyl chloride. The case of an hepatic angiosarcoma which

Noncirrhotic portal hypertension after arsenic ingestion.

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Five years after arsenic therapy, the patient described had noncirrhotic portal hypertension, for which he had splenectomy and anastomosis of the splenic vein to the left renal vein. During the 12-year postoperative period he had Bowen's disease (skin carcinoma), but has had normal liver function
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