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neuroectodermal tumors primitive/protease

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ArtiklerKliniske studierPatenter
4 resultater

Mutation analysis and loss of heterozygosity of PEDF in central nervous system primitive neuroectodermal tumors.

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Deletion of 17p is the most frequent abnormality observed in central nervous system (CNS) primitive neuroectodermal tumors (PNETs), implicating the presence of a tumor suppressor gene which maps to 17p. The gene for pigment epithelium-derived factor (PEDF) has been cloned and mapped to 17p13. PEDF

Protein Profiling of the Supratentorial Primitive Neuroectodermal Tumor (PNET) Cell Line PFSK-1.

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Supratentorial primitive neuroectodermal tumors (PNETs) are rare embryonal cerebral hemispheric tumors proposed to arise from primitive neuroepithelial cells. The permanent cell line PFSK-1 is widely used in studies of this tumor entity and it was the aim of this study to generate a

Successful treatment of primitive neuroectodermal tumor-associated microangiopathy with multiple bone metastases.

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We report here a 16-year-old male with primitive neuroectodermal tumor (PNET)-associated probable microangiopathy with multiple bone metastases. Laboratory findings excluded the possibility of amegakaryocytic or immune thrombocytopenia and/or disseminated intravascular coagulation. He was first
Patients with primary brain tumors have bleak prognoses and there is an urgent desire to identify new markers for sensitive diagnosis and new therapeutic targets for effective treatment. A family of proteins, the disintegrin and metalloproteinases (ADAMs or adamalysins), are cell surface and
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