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otitis media/albumin
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Round window membrane permeability to human serum albumin in antigen-induced otitis media.
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The round window membrane (RWM) permeability to human serum albumin (HSA) was investigated in both normal chinchillas and chinchillas sensitized with HSA. The effect of a corticosteroid agent (triamcinolone) on the RWM permeability was also analyzed. It was found that HSA could not be detected in
Passage of albumin from the middle ear to the inner ear in otitis media in the chinchilla.
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A study of the permeability of the middle ear-inner ear interface for macromolecules was carried out in chinchillas with open and obstructed eustachian tubes utilizing tritiated human serum albumin and immunoelectrophoresis. Tritiated albumin was placed in the round window niche area or normal
Characterization of otitis media with effusion based on the ratio of albumin and immunoglobulin G concentrations in the effusion.
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OBJECTIVE
To characterize the groups of middle ear effusions (MEE) defined on the basis of the ratio of albumin and immunoglobulin G concentrations (A/G) in the effusion and to identify the correlation between these groups of MEE and the clinical features of otitis media with effusion
[Experimental study on allergic otitis media. 1. Allergenic effect of Proteus vulgaris on guinea pigs sentitized with egg albumin].
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Local production of IgG to pneumococcal C-polysaccharide in upper airway secretions from children with recurrent acute otitis media.
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Antibodies against C-polysaccharide (C-Ps), a common cell wall component of all pneumococci, may be of importance for the elimination of decaying pneumococci. By means of ELISA with phenylated C-Ps, anti-C-Ps IgG was measured in samples of plasma and upper airway secretions from otitis-prone
Serum albumin, retinol-binding protein, thyroxin-binding prealbumin and acute phase reactants as indicators of undernutrition in children with undue susceptibility to acute infections.
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This study was conducted in order to test the usefulness of measuring the concentrations of selected serum proteins and acute phase reactants in assessing the nutritional status of children with undue susceptibility to acute infections. The concentrations of serum proteins were determined by an
Otitis media with effusion in an allergic animal model: A functional and morphological study.
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OBJECTIVE
Allergy is considered as one of important etiologic factor of otitis media with effusion (OME). In present study, we evaluated the causal effect of allergy on OME in an animal model, and investigated the secondary effect of bacterial infection.
METHODS
Allergy and control animals were
Nasopharyngeal secretory immunoglobulins in children with recurrent acute otitis media and secretory otitis media.
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Secretory IgA (SIgA) and secretory IgM (SIgM), total IgA and total IgM were measured in plasma and nasopharyngeal secretions (NPS) from young children with different degrees of otitis proneness. Significantly higher levels of plasma IgM and lower levels of NPS-SIgM were found in children with
Bile acids identified in middle ear effusions of children with otitis media with effusion.
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OBJECTIVE
Several studies have shown the presence of pepsin in the middle ear effusions of children with otitis media with effusion (OME). When gastric reflux is the cause, other noxious reflux products might be present. We therefore investigated the presence of bile acids in the middle ear
Sequential analysis of serum proteins in middle ear effusions. A study in rats with experimentally induced serous and purulent otitis media.
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Two otomicroscopically well-defined types of otitis media (OM)--one culture-negative serous (SOM) and the other purulent (POM)--were induced in rats by mechanically obstructing the eustachian tube or by splitting the soft palate. Samples of middle ear effusions (MEE) produced and sera were
Antioxidant role of selenium in rats with experimental acute otitis media.
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The aim of this prospective experimental animal study was to determine whether selenium had a protective effect on oxidative stress in rats with acute otitis media, by measuring the alterations of antioxidant parameters and lipid peroxidation on days 4 and 10 after inoculation into the middle ear.
Our experience on the management of acute mastoiditis in pediatric acute otitis media patients
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Objective: The incidence of complications due to acute otitis media (AOM) in childhood has decreased significantly with the use of new antibiotics in recent years. However, acute mastoiditis (AM) is still the most common complication that
Investigation of antioxidant status in children with acute otitis media and tonsillitis.
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OBJECTIVE
Antioxidant enzymes status was investigated in children with acute otitis media (AOM) and acute tonsillitis. The aim was to determine the effect of oxidative damage due to free radicals on the antioxidant enzymes status in children with AOM and acute tonsillitis.
METHODS
We measured
Morphologic and biochemical study of vascular permeability of the middle ear mucosa in experimental otitis media.
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The vascular permeability of the middle ear mucosa of chinchillas was examined by light and electron microscopy using horseradish peroxidase (HRP). Two kinds of experimental otitis media were used: serous otitis media (SOM) produced by eustachian tube obstruction and purulent otitis media (POM)
Transcription of genes encoding iron and heme acquisition proteins of Haemophilus influenzae during acute otitis media.
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Unencapsulated Haemophilus influenzae is the second most common etiologic agent of otitis media in children. H. influenzae requires heme for aerobic growth in vitro and is able to utilize hemoglobin and complexes of heme-hemopexin, heme-albumin, and hemoglobin-haptoglobin and ferritransferrin as
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