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Effects of Structured Exercise Regime in Gestational Diabetes Mellitus

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StatusRekrutacyjny
Sponsorzy
Foundation University Islamabad

Słowa kluczowe

Abstrakcyjny

Rehabilitation in the field of Obstetrics is an emerging field worldwide although it is still very much neglected in a country like Pakistan. Increasing prevalence of GDM has highlighted the importance of rehabilitation in this specific area. In USA upto14% of pregnancies get GDM problem, 6.8 to 10.4 % in China while in India 27.5% which is exceptionally high. Similarly in Pakistan it has become a common issue.
Many observational studies have been done to find the risk factors and causes of GDM. However to the best of investigator's knowledge no experimental study have been done so far on the effects of exercise on physical, physiological and psychological aspects of GDM. Hence a randomized control trial is planned on diagnosed GDM patients in Fauji Foundation Hospital Rawalpindi who will recieve supervised structured exercise regeme for 5 weeks and their data will be recorded using reliable tools at the baseline and after 5 weeks to assess the effects of exercise.

Opis

GDM is a medical condition of high maternal glucose level which is diagnosed only when women are pregnant and overcome after pregnancy. It results in various maternal and neonatal complications like caeserean delivery in mothers and obesity in children. Women having GDM have greater risk of diabetes and cardiovascular problems later in life which is threatening for us. Obese women are at increased risk of developing GDM and it is also a risk factor for developing high blood pressure and protein in the urine after 20 weeks of pregnancy that condition is known as preeclampsia.

Many studies have shown that physically active women are less prone to develop GDM as compare to those women who have sedentary life style which draws attention towards the role of antenatal exercises for prevention and management of GDM and has become the first line treatment in developed countries. In addition to obesity and sedentary life style other known risk factors are family history, age of mother and number of children but there is no definite single cause of GDM yet discovered.

Exercises programs during pregnancy are not usually practiced in our population and routine domestic activities are considered as enough for fitness. We have a common myth that pregnant women should not do treadmill or stationary cycle or any other aerobic activity which is really wrong and resulting in problems like GDM. Women following moderate exercise programs during their pregnancy have reported reduction in daily insulin administration dosage in comparison with women not doing any prescribed exercise. As Gestational weight gain is a major risk factor for GDM, exercises have given evidence to facilitate weight reduction.

Exercise programs prescribed by physical therapists during pregnancy for preventing and managing GDM are considered useful and recommended by researchers and practitioners around the world but in developing countries like Pakistan, women are not receiving this method of treatment due to lack of awareness in general public, lack of referral system from gynaecologists and obstetricians and unavailability of women health Physical therapists in hospital set ups.

This study will provide data showing the effects of exercise in biomarkers level and give the option of treatment to obstetricians.

This will fill the research gap in the area of rehabilitation in GDM. This will also highlight the importance of women health physical therapists in obstetric conditions as there is less awareness of this speciality in Pakistan.

This will provide the data regarding which type, intensity and duration of exercise should be recommendable while treating GDM.

This study will open new doors for researchers to do long term studies on different biomarkers with different exercise types.

Daktyle

Ostatnia weryfikacja: 09/30/2019
Pierwsze przesłane: 08/25/2019
Szacowana liczba przesłanych rejestracji: 10/28/2019
Wysłany pierwszy: 10/30/2019
Ostatnia aktualizacja przesłana: 10/28/2019
Ostatnia opublikowana aktualizacja: 10/30/2019
Rzeczywista data rozpoczęcia badania: 03/11/2019
Szacowana data zakończenia podstawowej działalności: 01/31/2020
Szacowana data zakończenia badania: 01/31/2020

Stan lub choroba

Gestational Diabetes Mellitus

Interwencja / leczenie

Other: Structured Exercise Group

Behavioral: Control treatment for both groups

Faza

-

Grupy ramion

RamięInterwencja / leczenie
Experimental: Structured Exercise Group
Structured Exercise Group will receive medical and dietary interventions like insulin plus structured aerobic exercise regime of moderate intensity by using stationary cycle (3-5 MET) 10 min, brisk walk 10 min The combination of Stabilization exercise (10 repetitions) and PFM training ( 20 repetitions set). Relaxation therapy including Mitchells physiological relaxation technique (10 repeatitions) alongwith deep breathing exercises. Life style modification with postural guidance and back care would also be followed. Exercise dosage would be twice a week for 05 weeks while exercise duration will be 45 to 50 min session under Physio supervision and home plan of 10 min exercise daily. Total 150 min per week. Data will be recorded at baseline then after treatment of 5 weeks.
Other: Structured Exercise Group
Structured aerobic exercise regime of moderate intensity by using stationary cycle (3-5 MET) 10 min, brisk walk 10 min. The combination of Stabilization exercise (10 repeatitions) and PFM training ( 20 repeatitions set). Relaxation therapy including Mitchells physiological relaxation technique (10 repetitions) along with deep breathing exercises.
Active Comparator: Control Group
Control Group will receive no structured exercise regime only the group will be receiving medical and dietary interventions like insulin in addition of the postural education and back care from Physical Therapist due to ethical concerns and their outcomes will be observed at the baseline and then after 05 weeks.

Kryteria kwalifikacji

Wiek kwalifikujący się do nauki 20 Years Do 20 Years
Płeć kwalifikująca się do naukiFemale
Przyjmuje zdrowych wolontariuszytak
Kryteria

Inclusion Criteria:

1. Women with age of 20 to 40 years and gestational age more than 20 weeks.

2. Diagnosed Gestational diabetes mellitus patients

3. Must be able to do 6 min walk test and lie under severity level 6 on the 0-10 Borg scale of breathlessness -

Exclusion Criteria:

1. Diagnosed neurological and cardiopulmonary problems.

-

Wynik

Podstawowe miary wyników

1. HbA1c [5 weeks]

HbA1c will be assessed at the base line and at the end of 5 weeks session. Lower score shows better outcome.

2. Blood Pressure [5 weeks]

Change in the Values of Blood pressure will be assessed at base line and at the end of 5 weeks session.

3. Lipid profile [5 weeks]

Lipid profile will be assessed at the base line and at the end of 5 weeks session

4. Renal function test (RFT) [5 weeks]

RFT will be assessed at the base line and at the end of 5 weeks session. Lower score shows better outcome.

5. C reactive protein [5 weeks]

C reactive protein will be assessed at the base line and at the end of 5 weeks session. Lower score shows better outcome.

6. Heart rate [5 weeks]

Change in the heart rate will be assessed at base line and at the end of 5 weeks session.

7. Respiratory rate [5 weeks]

Change in the respiratory rate will be assessed at base line and at the end of 5 weeks.

8. Blood glucose level [5 weeks]

Change in the blood glucose level will be assessed at base line and at the end of 5 weeks session.

Miary wyników wtórnych

1. Gestational weight gain [5 weeks]

Gestational weight gain by recording weight of women in pounds and gestational age in weeks at baseline and then after 5 weeks.

2. Edinburgh Post Natal Depression scale (Punjabi version) [5 weeks]

The score of Depression using Edinburgh Post Natal Depression scale (Punjabi version). Each answer is given on a score of 0-3 . Maximum score is 30 A score of 10 or higher indicates that depressive symptoms have been

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