it included 32 patients with acute ischemic stroke beyond the time of window (more than 6 hours) assigned to mechanical thrombectomy) plus the conventional treatment (Aspirin 150 mg and atorvastatin 40 mg).

it included 25 patients with acute ischemic stroke beyond the time of window (more than 6 hours) who received medical treatment (Aspirin 150 mg and atorvastatin 40 mg).

Acute Ischemic Stroke

Transfemoral a microcatheter with its distal end was positioned a few millimeters beyond the distal aspect of the clot, the guide wire was exchanged by Solitaire stent device. The device was held in place when 3 mm was out of the microcatheter. The microcatheter was slowly pulled back to deploy the TR or ST device over the clot.

thrombectomy

medical treatment (Asprin, statin, nootropic drug)

non intervention group

Ahmed El-Bassiony

Abdalla Khalil

Mechanical Thrombectomy in Acute Ischemic Stroke Beyond the Time of Window

Mechanical Thrombectomy in Acute Ischemic Stroke Beyond the Time of Window: Non Randomized Controlled Clinical Trial

1- Measuring the Modified Rankin Score (MRS) on day 90 (ranging from, 0 to 6, with higher scores indicating greater disability). Favorable outcome was defined as achieving functional independence (mRS of 0,1or 2) poor outcome was defined as MRS of 3-5.

2- Changes in National Institute of Health Stroke Scale (NIHSS) were also measured at baseline (pre-thrombectomy) and on day 90. Favorable outcome when the score decrease by 4 or more point of the score.

1-Estimate the number and percent of patients who have vascular recanalization according to thrombolysis in cerebral ischemia (TICI) score. TICI categories span from no perfusion (grade 0) to complete perfusion (grade 3). The "partial perfusion" category (grade 2) is defined as cases in which contrast passes the obstruction but with rates of entry and wash-out slower than normal and is subdivided into 2 subcategories, 2a and 2b. Successful vascular recanalization was defined as TICI grade 2b to 3.

2-estimate the number of patients who developed complication death (mRS=6) symptomatic intracerebral hemorrhage, and arterial dissection.

Eman M. Khedr

Professor of Neurology

Assiut University

Ain Shams University

Aswan University

Ondansetron 8Mg/4mL Injection: administration of a bolus of 8 mg intravenous Ondansetron diluted in 10 ml of saline solution (0,09%) 5 minutes before spinal anesthesia

administration of 10 ml of saline solution (0,09%) 5 minutes before spinal anesthesia

Ondansetron

Cesarean Section

Spinal Anesthesia

Hemodynamics

investigators administrated intravenously Ondansetron 8 mg 5 minutes before spinal anesthesia.

Ondansetron 8Mg/4mL Injection

Mahdia University Hospital

Ministry of Health

Effects of Ondansetron on Hemodynamics in Cesarean Section Under Spinal Anesthesia

Effects on Ondansetron on Maternal Hemodynamics After Cesarean Section Under Spinal Anesthesia: a Randomized Controlled Trial

decrease of systolic blood pressue with more than 25% from baseline values

decrease of cardiac output (contious non invasive estimation of cardiac output based on pulse wave transit time) with more than 15% from baseline values

ephedrine dose used in perioperative time

Majdoub Ali MD

clinical professor

University Hospital, Mahdia

Ondansetron group (group O): 8mg(10 ml) of Ondansetron administrated 5 minutes before spinal anesthesia control group (group C): saline solution 0,9%(10ml)

an anesthesia nurse ; not included in the analysis, verified the allocation and prepared the syringe fulled with ondansetron or saline solution

alpha glucose/krwotok

Mechanical Thrombectomy in Acute Ischemic Stroke Beyond the Time of Window

Effects of Ondansetron on Hemodynamics in Cesarean Section Under Spinal Anesthesia

Impact of Antenatal Betamethasone on Plasma Glucose Levels

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