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Metabolic syndrome and low-grade systemic inflammation are associated with knee osteoarthritis (OA), but the relationships between these factors and OA in other synovial joints are unclear. The aim of this study was to determine if a high-fat/high-sucrose (HFS) diet results in OA-like
A high-sucrose diet induces insulin resistance and dyslipidemia in normal rats. The purpose of the present study was to investigate effects of a high-sucrose diet to glycolipid metabolism in Zucker Diabetic Fatty (ZDF) rat. Male ZDF rats were fed with a high-sucrose (68%) diet from 6 to 18 weeks of
Obesity is associated with metabolic dysfunction, including insulin resistance and hyperinsulinemia, and with disorders such as cardiovascular disease, osteoporosis, and neurodegeneration. Typically, these pathologies are examined in discrete model systems and with limited temporal resolution, and
BACKGROUND
Otsuka Long-Evans Tokushima fatty (OLETF) rats are an established model of diabetic nephropathy. However, diabetes and diabetic nephropathy (DN) in OLETF rats develop later than in other animal type 2 diabetes models.
OBJECTIVE
This study was conducted to investigate the serial changes in
Axoplasmic changes were studied in the saphenous nerve of the albino rat during the early stages of Wallerian degeneration. The axons were examined at 0, 24, and 48 hours after the surgical transection of the nerve. The material was fixed in 2 per cent OsO(4) in phosphate buffer (pH 7.2-7.5) with
The high metabolic rate of harvested asparagus spears (Asparagus officinalis L.) causes rapid deterioration. To extend shelf life, we investigated the effect of sucrose treatment on asparagus during storage. Asparagus spears were treated with 3%, 5%, and 10% sucrose and stored at 2 °C for 20 h.
The effects of obesity on different musculoskeletal tissues are not well understood. The glycolytic quadriceps muscles are compromised with obesity, but due to its high oxidative capacity, the soleus muscle may be protected against obesity-induced muscle damage. To determine the time-course
Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by
Sucrose absorption was studied by the Breath Test method (BTH) in 41 infants presenting with acute diarrhea. In 28, studies were performed in children treated orally with a 40% sucrose solution. Malabsorption was demonstrated in 8 cases. In 36 infants, sucrose loading test (1 g/kg) was carried out
Progressive decline of islet beta cell mass is a hallmark of type 2 diabetes, where nutritional insults are invoked in the pathologic process. Its detailed mechanisms are, however, incompletely understood. We explored the effect of sucrose diet on mitochondria in Goto Kakizaki (GK) rats, a
OBJECTIVE
To evaluate the effects of sucrose treatment on the formation of granulation tissue in a standard wound model.
METHODS
Animal study.
METHODS
University hospital, Finland.
METHODS
32 male Sprague-Dawley rats divided into 4 groups.
METHODS
Implantation of viscose cellulose sponge
BACKGROUND
Different theories have been presented to explain how atrophic gastritis may lead to gastric cancer development. One contributing factor could be impaired function of the gastric mucosal barrier. The aim of this study was to investigate if there are changes in gastric mucosal permeability
When subjected to increasing pressure at 0 degree C, rat liver mitochondria become permeable to sucrose, causing them to swell and their outer membrane to rupture. Afterwards they are lysed and their matrix content is released into the medium. This permeation to sucrose may be prevented to some