Lateral Neck Sentinel Lymph Node Biopsy(LSLNB)in PTC
Palavras-chave
Resumo
Descrição
On the day of the operation, patients underwent preoperative lymphoscintigraphy after the intratumoral injection of a Tc-99m phytate 1 mCi in 0.1-0.2 mL 0.9% NaCl under ultrasonographic guidance. Total thyroidectomy or lobectomy with central neck dissection preceded SLN detection to avoid interference by primary tumor radioactivity. After total thyroidectomy or lobectomy, the dissections were performed toward the internal jugular chain beneath the sternocleidomastoid muscle. A handheld, collimated gamma probe and lymphoscintigraphy were used to scan the lateral compartments (through skin and under the SCM) for "radioactive" lymph nodes. Removed SLNs were submitted immediately for frozen biopsy. If any of the SLNs were positive for metastasis on the frozen sections, MRND was performed immediately. In cases for which the frozen section was negative but the final pathology report detailed microscopic positivity in the lateral sentinel nodes, RAI ablations were performed without additional MRND.
datas
Última verificação: | 03/31/2016 |
Enviado pela primeira vez: | 06/01/2010 |
Inscrição estimada enviada: | 06/02/2010 |
Postado pela primeira vez: | 06/03/2010 |
Última atualização enviada: | 04/19/2016 |
Última atualização postada: | 04/20/2016 |
Data real de início do estudo: | 05/31/2009 |
Data Estimada de Conclusão Primária: | 12/31/2010 |
Data Estimada de Conclusão do Estudo: | 12/31/2010 |
Condição ou doença
Intervenção / tratamento
Procedure: Lateral sentinel group
Fase
Grupos de Armas
Braço | Intervenção / tratamento |
---|---|
Active Comparator: Lateral sentinel group Lateral sentinel lymph node biopsy with radioisotope | Procedure: Lateral sentinel group Sentinel lymph node biopsy with radioisotope. Isotope injection and lymphoscintigraphy preoperatively |
No Intervention: No intervention for lateral neck No lateral sentinel lymph node biopsy with radioisotope |
Critério de eleição
Idades qualificadas para estudar | 18 Years Para 18 Years |
Sexos elegíveis para estudo | All |
Aceita Voluntários Saudáveis | sim |
Critério | Inclusion Criteria: - Cases with tumors larger than 1 cm in size or with suspicious central neck node metastasis in Papillary thyroid cancer Exclusion Criteria: - The patient with definite metastatic lymph node in lateral neck compartment |
Resultado
Medidas de Resultado Primário
1. The usefulness of lateral sentinel lymph node biopsy in PTC [at Oct 2011]