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OBJECTIVE To identify factors associated with incident metabolic and reproductive adverse events in children and adolescents. METHODS A retrospective cohort design evaluating Medicaid medical and pharmacy claims made in South Carolina between January 1996 and December 2005 was employed for 3,657

Add-on topiramate reduces weight in overweight patients with affective disorders: a clinical case series.

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BACKGROUND The weight-gain caused by many psychotropic drugs is a major cause for poor compliance with such medications and could also increase cardio-vascular morbidity among psychiatric patients. Recent reports have shown that the anticonvulsant topiramate causes weight loss in various patient

Blood levels and management of lithium treatment.

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The limited value of plasma measurements in the management of treatment with lithium is discussed in the light of the mechanisms of its therapeutic actions and toxic effects.The plasma level of lithium usually rises twofold or threefold in the three to five hours after ingestion of each dose of

Adverse events associated with psychotropic treatment in African American children and adolescents.

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To identify the types of adverse events associated with psychotropic treatment in African American children and adolescents, analyses were performed using a retrospective cohort design evaluating medical and pharmacy claims from South Carolina's Medicaid program covering outpatient and inpatient

Diagnosing and treating comorbid (complicated) bipolar disorder.

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Comorbidity is the rule, not the exception, in bipolar disorder. The most common mental disorders that co-occur with bipolar disorder in community studies include anxiety, substance use, and conduct disorders. Disorders of eating, sexual behavior, attention-deficit/hyperactivity, and impulse

Aripiprazole: initial clinical experience with 142 hospitalized psychiatric patients.

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BACKGROUND Aripiprazole is the first dopamine D2 receptor partial-agonist approved for treatment of schizophrenia. Its apparently benign adverse-effect profile encourages broader use in other disorders, especially to limit weight gain associated with other antipsychotic or antimanic agents. We
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