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The Effect on Anxiolytics With Type of Antiemetic Agents on Postoperative Nausea and Vomiting in High Risk Patients

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This prospective study evaluates female, nonsmoking patients undergoing laparoscopic cholecystectomy. The patients are randomly allocated to either group MR (midazolam 0.05mg/kg with ramosetron 0.3mg) or group MP (midazolam 0.05mg/kg with palonosetron 0.075mg). The incidence of PONV, severity of

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

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Patients included in this dose-finding study will be enrolled consecutively after consent and verification of the selection criteria, with a minimum of 24 hours after completion of previous patient follow-up. Prior to the administration of morphine, the following exams will be performed: clinical,

The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients

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Sufentanil, unlike morphine and hydromorphone, avoids the issue of active metabolites that can lead to prolonged, untoward effects, which can complicate postoperative care and affect patient discharge. One study found that sufentanil SL 30 mcg was well tolerated, with no unexpected adverse events,

Interest of Audiovisual Distraction in the Management of Anxiety and Pain During Oocyte Retrieval

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Consent female patients between 18 and 43 years old scheduled for oocyte retrieval will be enrolled in this study and their anxiety level will be collected via a questionnaire. After randomization, patients will either benefit from audiovisual distraction using HappyMed Video Glasses, (medical

The Use of ADV6209 for Premedication in Pediatric Anesthesia

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Premedication represents an important part in the perioperative management of children and is used to reduce pre-operative stress as well as to facilitate induction of inhaled anaesthesia. Midazolam is the drug most often used for premedication in infants and children because it provides good

Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?

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1. Introduction Patients generally experience high levels of anxiety when are hospitalized to undergo surgery and other invasive procedures. Anxiety is an emotional state or condition characterized by stress and unpleasant feelings. Awake patients in the operating theatre are afraid of they will

Midazolam Versus Dexamethasone-ondansetron in Preventing Postoperative Nausea-vomiting for Laparoscopic Surgeries

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After Institutional Ethical Committee approval and written informed consent, 120 adult patients will be recruited for the study if they satisfy the inclusion and exclusion criteria as mentioned later. Consent will be obtained from the patients themselves. Standard protocol for administration of

Oral Dexmedetomidine for Parental Separation in Pediatrics Undergoing Adenotonsillectomy

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After obtaining approval from the research Ethics Committee of the Suez Canal University Hospitals and written informed consent from the parents of each participant, 74 American Society of Anesthesiologists (ASA) physical status I and ІІ children aged 3-10 years scheduled for adenotonsillectomy

Add-on Methotrexate for the Treatment of Schizophrenia

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OBJECTIVES The objective of the study is to evaluate the efficacy of Methotrexate compared to placebo, as add-on to anti-psychotics in the treatment of patients with schizophrenia or schizoaffective disorder. ENDPOINTS Primary outcome measure: PANSS positive score at the end of the trial. Secondary

A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation

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Intravenous sedation (IVS) is an integral aspect of the oral and maxillofacial surgeon's practice. For many minor oral surgical procedures, intravenous sedation is often necessary to manage patient anxiety and discomfort, while also facilitating a safe and efficient procedure in the outpatient

Enhanced Recovery Strategies in Elective Breast Surgery

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Bilateral breast reduction and bilateral breast augmentation are both routine plastic surgery procedures commonly performed on an outpatient basis. While patient satisfaction following these procedures is high, postoperative pain management can be challenging, resulting in decreased patient

Added Conversational Hypnosis Reduced General Anesthesia Side Effects for Day Case Breast Surgery

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Drug premedication with anxiolytics (benzodiazepine or equivalent) are usually prescribed to alleviate patient anxiety. However, alternative techniques, additional non-pharmacological, have proven effective in alleviating pain and anxiety perioperative. These techniques are retained relaxation

Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty

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Introduction Various adjuvants like morphine, fentanyl, clonidine, ketamine are being used since long for improvement of intraoperative anaesthesia and postoperative analgesia following spinal anaesthesia. On the other hand, such adjuvants have their associated adverse effects. As a result, search

Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease (AD) (THC-AD)

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Alzheimer's disease (AD) is the most prevalent neurodegenerative disease of aging, affecting an estimated 5.2 million Americans and predicted to increase to 13.8 million by 2050. AD affects both cognition and emotion. Neuropsychiatric symptoms (NPS) in AD are a major cause of burden to patients,

Pain Medications in Children Undergoing Strabismus Surgery

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Research Design This is a randomized clinical trial with masked assessment, comparing recovery indices for patients receiving longer acting versus shorter acting opiate analgesia using hydromorphone or fentanyl as intraoperative analgesics. An otherwise standardized anesthetic and analgesic regimen

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