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artemisinin/cancro
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Treatment of viral tumors and hemorrhoids with artemisinin and derivatives
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BACKGROUND OF THE INVENTION
This invention relates to the topical and/or systemic treatment of viral-induced skin tumors and hemorrhoids with a class of compounds having sesquiterpene structures, including artemisinin, dihydroartemisinin, and derivatives and analogs of these compounds.
Currently
Methods of treating cancer using a combination of an immunomodulatory compound and an artemisinin or a derivative thereof
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1. FIELD
Provided herein are methods of treating cancer by administering immunomodulatory compounds in combination with other compounds.
2. BACKGROUND
Herbal remedies involving the Sweet wormwood (Artemisia annua) have been traditionally used in China as a treatment for a variety of ailments,
Use of artemisinin for treating tumors induced by oncogenic viruses and for treating viral infections
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BACKGROUND
Despite the advent of the Papanicolaou (Pap) smear, cervical cancers and pre-cancers remain important health problems for women, especially in poorly monitored women in the United States and developing countries. Worldwide, 250,000 women die annually from this cancer. Cervical dysplasia
Use of artemisinin for treating tumors induced by oncogenic viruses and for treating viral infections
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BACKGROUND
Despite the advent of the Papanicolaou (Pap) smear, cervical cancers and pre-cancers remain important health problems for women, especially in poorly monitored women in the United States and developing countries. Worldwide, 250,000 women die annually from this cancer. Cervical dysplasia
Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer
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BACKGROUND OF THE INVENTION
Artemisinin is a sesquiterpene lactone isolated from the plant Artemisia annua L, extracts, which has been used to treat malaria and a variety of other ailments for nearly 2000 years. Artemisinin and its derivatives, such as dihydroartemisinin, artemether, artesunate,
Use of artemisinin for treating tumors induced by oncogenic viruses and for treating viral infections
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BACKGROUND
Despite the advent of the Papanicolaou (Pap) smear, cervical cancers and pre-cancers remain important health problems for women, especially in poorly monitored women in the United States and developing countries. Worldwide, 250,000 women die annually from this cancer. Cervical dysplasia
Dimeric derivatives of artemisinin and application in anti-cancer therapy
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The present invention relates to dimeric derivatives of 10-trifluoromethylartemisinin linked on the one hand by a carbon in position 10 and on the other hand by a carbon in position 16, and also to the use of same for treating cancer.
The cytotoxic properties of artemisinin derivatives were shown in
1,2,3-triazole containing artemisinin compounds and process for preparation thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a national phase of International Patent Application No. PCT/IN2012/000099, filed Feb. 14, 2012, which claims priority to Indian Patent Application No. 366/DEL/2011, filed Feb. 14, 2011.
FIELD OF THE INVENTION
The invention relates
Series of artemisinin derivatives and process for preparation thereof
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is the national phase under 35 U.S.C. .sctn.371 of PCT International Application No. PCT/IB2011/000078, filed Jan. 20, 2011, which claims the benefit of Indian Patent Application No. 172/DEL/2010, filed Jan. 22, 2010, the entire contents of
Artemisinin compounds and synthesis and use thereof
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FIELD OF THE DISCLOSURE
The present disclosure describes artemisinin monomers and dimers, and methods of synthesis and use thereof. Methods of synthesis include use of the Ugi reaction and methods of use include treating cancers, parasitic infections and yeast infections.
BACKGROUND OF THE
Two-carbon linked artemisinin-derived trioxane dimers
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BACKGROUND
As the landscape of therapeutic treatment advances, orally available small molecule inhibitors remain a prominent weapon in the fight against disease. Perhaps nowhere is this approach more important than in the treatment of malaria, whose parasites infected over 200 million people and
Treatment of skin diseases with artemisinin and derivatives
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BACKGROUND OF THE INVENTION
This invention relates to the topical and/or systemic treatment of psoriasis, ultraviolet radiation-induced skin diseases and skin tumors, and other related conditions with a class of compounds having sesquiterpene structures, including artemisinin, dihydroartemisinin,
Methods of inhibition or killing cancer cells using an endoperoxide
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FIELD OF THE INVENTION
The present invention relates to the inhibition or killing of cancer cells. More particularly, the present invention relates to the systemic and topical treatments of cancer cells with sesquiterpene compounds.
BACKGROUND OF THE INVENTION
Artemisinin (Qinghaosu) and its analogs
Suppression and prevention of tumors
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BACKGROUND OF THE INVENTION, FIELD OF THE INVENTION
The invention relates to improvements in minimizing the chances of the occurrence of malignant tumors (cancers) and/or the reduction in the severity of harm from existing malignant tumors, including methods, articles, etc. for providing treatments;
Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the formation of a novel, stable C-10 carba trioxane dimer that may easily be transformed into different trioxane dimers. Some of these dimers are 10 times more antimalarially potent in vitro than artemisinin.
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