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beta ionone/cancro do pulmão
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6 resultados
Antiproliferative and antioxidant potential of beta-ionone against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.
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Nowadays, in developing countries like India, incidence of lung cancer is increasing rapidly, and as a consequence it has become the most common cause of malignancy-associated death. This study is aimed to evaluate the therapeutic efficacy of beta-ionone (ION), a precursor for carotenoids against
β-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents.
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A series of endoperoxides (3a-j) were synthesized and evaluated for cytotoxic activity against four human cancer cell lines by using SRB dye assay. All the compounds displayed moderate to high cytotoxic effect against almost all investigational cancer cells. Particularly, compounds bearing electron
Cows' milk fat components as potential anticarcinogenic agents.
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The optimum approach to conquering cancer is prevention. Although the human diet contains components which promote cancer, it also contains components with the potential to prevent it. Recent research shows that milk fat contains a number of potential anticarcinogenic components including conjugated
Beta-carotene degradation products - formation, toxicity and prevention of toxicity.
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Carotenoids are widely used as important micronutrients in food. Furthermore, carotenoid supplementation has been used in the treatment of diseases associated with oxidative stress such as various types of cancer, inflammatory diseases or cystic fibrosis. However, in some clinical studies harmful
Beta-carotene cleavage products induce oxidative stress in vitro by impairing mitochondrial respiration.
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Carotenoids are widely used as important micronutrients in food. Furthermore, carotenoid supplementation has been used in the treatment of diseases associated with oxidative stress. However, in some clinical studies harmful effects have been observed, for example, a higher incidence of lung cancer
Antioxidant and pro-oxidant effects of lycopene in comparison with beta-carotene on oxidant-induced damage in Hs68 cells.
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Lycopene has become a focal point in recent research following clinical trials that suggest that beta-carotene may promote lung cancer in smokers. Because lycopene only differs from beta-carotene in lacking the beta-ionone structure, and beta-carotene is known to have pro-oxidant activity in vitro,
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