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Oxidative Stress and Apoptosis of Gaeumannomyces graminis (Get) Induced by Carabrone.
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Carabrone is isolated from Carpesium macrocephalum Franch. et Sav, which has good fungicidal activity, especially for Gaeumannomyces graminis (Get). According to previous studies, we speculated that carabrone targets the mitochondrial enzyme complex III of Get. To
[Study on Chemical Constituents from Carpesium abrotanoides].
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OBJECTIVE
To study the chemical constituents from Carpesium abrotanoides.
METHODS
Compounds were isolated and pu- rified by silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis.
RESULTS
Ten compounds were isolated and identified as
Cytotoxic sesquiterpene lactones from Carpesium abrotanoides.
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Eight sesquiterpene lactones, 4 alpha,5 alpha-epoxy-10 alpha,14-dihydro-inuviscolide (1), 2,3-dihydroaromomaticin (2), carpesiolin (3), carabrone (4), carabrol (5), telekin (6), ivalin (7) and 11,13-didehydroivaxillin (8), were isolated from the aerial parts of Carpesium abrotanoides Linne
[Simultaneous determination of five sesquiterpene lactones in Carpesium abrotanoides by HPLC].
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An HPLC method was established to simultaneously determine the five sesquiterpene lactones, carabrone, carabrol, 2-desoxy-4-epi-pulchellin, telekinand 11(13)-dehydroivaxillin in Carpesium abrotanoides. Samples were analyzed on a kromasil C18 column (4.6 mm x 250 mm, 5 µm); mobile phase: A was
[Studies on sesquiterpene lactones from Carpesium faberi].
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By using various chromatographic techniques,18 sesquiterpene lactones were isolated from the acetone extract of Carpesium faberi. Their structures were identified on the basis of comprehensive spectroscopic data, involving 2 carabrane sesquiterpenoids [carabrone(1), 4R-carabrol(2)], 3 eudesmane
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