Participants will be dosed 250mg acetazolamide (p.o.) three times per day for two days prior to and a single dose on the morning of the experimental day.

Participants will be dosed 100mg Methazolamide (p.o.) two times per day separated by a placebo dose for two days prior to and a single dose on the morning of the experimental day. The placebo dose is used to match the timing and number of pills taken between all arms of the study.

Participants will take three placebo pills per day for two days prior to and a single dose on the morning of the experimental day.

Hypoxia

Acetazolamide

100mg, taken orally two times per day. A placebo pill will be taken between each dose of methazolamide to match the timing of doses and the number of pills between study arms.

Methazolamide

A placebo will be taken three times per day

Placebo

University of British Columbia

Muscle Fatigue and Carbonic Anhydrase Inhibitors

The Effect of Carbonic Anhydrase Inhibitors on the Pulmonary System Response to Muscle Fatigue.

Glen Foster

Assistant Professor

Patients over the age of 18 years with cystoid macular edema and retinal degeneration will be treated with Trusopt.

carbonic anhydrase/fadiga

Muscle Fatigue and Carbonic Anhydrase Inhibitors

Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration

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