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carpesium lipskyi/clorofórmio
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Sesquiterpene lactones from Carpesium rosulatum with potential cytotoxicity against five human cancer cell lines.
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In search for plant-derived cytotoxicity compound against human cancer cells (A549, SK-OV-3, SK-MEL-2, XF498, HCT15), it was found that the chloroform extracts obtained from the whole plant of Carpesium rosulatum MlQ. (Compositae) exhibited significant cytotoxic activity. Four sesquiterpene lactone,
Immunotoxic sesquiterpene lactone from Carpesium rosulatum Miq.
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The whole plants of Carpesium rosulatum were chloroform extracted and the isolated sesquiterpene lactones and immunotoxicity effects were studied. The structures and stereochemistry of these compounds were established on the basis of analysis of spectra including mp, [α](D)(25), IR, UV, EI-MS, MS,
Anticancer activity of sesquiterpene lactone from plant food (Carpesium rosulatum) in human cancer cell lines.
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In the search for anticancer compounds against human cancer cells (A549, SK-OV-3, SK-MEL-2, XF498, HCT15), it was found that the chloroform extracts obtained from the whole plant food of Carpesium rosulatum MlQ exhibited significant anticancer activity. The structures and stereochemistry of these
Compounds with antiproliferative activity on five human cancer cell lines from South Korean Carpesium triste.
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In the search for antiproliferative compounds against human cancer cells (A549, SK-OV-3, SK-MEL-2, XF498, HCT15), it was found that the chloroform extracts obtained from the whole plant of Carpesium rosulatum Miq. (Compositae) exhibited significant cytotoxic activity. Two sesquiterpene lactones,
Cytotoxic germacranolide sesquiterpene lactones from Carpesium triste var. manshuricum.
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Four known germacranolide sesquiterpene lactones, 2alpha,5-epoxy-5,10-dihydroxy-6alpha-angeloyloxy-9beta-isobutyloxy-germacran-8alpha,12-olide (1), 2alpha,5-epoxy-5,10-dihydroxy-6alpha,9beta-diangeloyloxy-germacran-8alpha,12-olide (2, divaricin B),
Antiplasmodial activity of ineupatorolides A from Carpesium rosulatum.
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Samples of Carpesium genus used as traditional remedies for the treatment of parasite infections were collected, and methanol extracts were obtained by sonication. The ethylacetate-, n-butanol- and H(2)O-soluble fractions exhibited weak antiplasmodial activity (IC(50) > 100 microg/ml; IC(50), 50%
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