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caulophyllum robustum/ataque cardíaco
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Profound neonatal congestive heart failure caused by maternal consumption of blue cohosh herbal medication.
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A newborn infant whose mother ingested an herbal medication, blue cohosh, to promote uterine contractions presented with acute myocardial infarction associated with profound congestive heart failure and shock. The infant remained critically ill for several weeks, although he eventually recovered.
Safety and efficacy of blue cohosh (Caulophyllum thalictroides) during pregnancy and lactation.
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BACKGROUND
There is a lack of basic knowledge on the part of both clinicians and patients as to the indications for use and safety of herbal medicines in pregnancy and lactation. This is one article in a series that systematically reviews the evidence for commonly used herbs during pregnancy and
Heart Toxicity Related to Herbs and Dietary Supplements: Online Table of Case Reports. Part 4 of 5.
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BACKGROUND
The purpose of this review was to create an online research summary table of heart toxicity case reports related to dietary supplements (DS; includes herbs).
METHODS
Documented PubMed case reports of DS appearing to contribute to heart-related problems were used to create a "Toxic Table"
Toxins in botanical dietary supplements: blue cohosh components disrupt cellular respiration and mitochondrial membrane potential.
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Certain botanical dietary supplements have been associated with idiosyncratic organ-specific toxicity. Similar toxicological events, caused by drug-induced mitochondrial dysfunction, have forced the withdrawal or U.S. FDA "black box" warnings of major pharmaceuticals. To assess the potential
Caulophine protects cardiomyocytes from oxidative and ischemic injury.
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Caulophine is a new fluorenone alkaloid isolated from the radix of Caulophyllum robustum MAXIM and identified as 3-(2-(dimethylamino) ethyl)-4,5-dihydroxy-1,6-dimethoxy-9H-fluoren-9-one. Due to its new chemical structure, the pharmacological activities of caulophine are not well characterized. The
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