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Safety of Nitroglycerin for Field Treatment of STEMI

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Nitroglycerin is widely used for treatment of chest pain of suspected cardiac etiology in the field. While there are a few studies from the pre-reperfusion era that demonstrate some benefit of nitroglycerin administration in patients with myocardial infarction, there are no studies establishing its
Patients presenting with NSTEMI who are scheduled to undergo elective cardiac catheterization and coronary angiography with primary PCI will be selected for participation in the study. The patients will undergo a clinically indicated resting non-contrast echocardiogram to assess LV function and

CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction

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The type of study that is being proposed is called a prospective, randomized, dose escalation study. This means that some of the patients will receive a solution which contains the cells and some of the patients will receive conventional medical treatment. The ratio is 2:1, which means that twice as
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