The present invention relates to the anticancer composition containing an effective amount of herbal extract, and more particularly to the anticancer composition containing an effective amount of extract of Salviae Miltiorrhizae Radix, Chrysanthemum indicum, Acanthopanax senticosus, Cinnamomum cassia Blume, Eucommia ulmoides Oliv., Glycyrrhiza uralensis Fisch, Pueraria thunbergiana Benth, Crataegus pinnatifida Bunge, Cassia tora, Carthamus tinctorius L., Paeonia lactiflora Pall, and Angelica gigas Nakai. The anticancer composition containing an effective amount of herbal extract has advantage of minimal or few side effects and cytotoxicity as compared to many existing anticancer drugs having cytotoxicity and side effects.

Lee; Jai-Heon

Kim; Kyoung-Sook

Lee; Young-Choon

Cho; Chang-Woo

Kim; KyoungMee

Chung; Young Soo

DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION

Anticancer composition containing herbal extract

What is disclosed in the invention is a preparation method of a supercritical Cinnamomum subavenium extract, which is made from the material, the dried stem of C. subavenium. The extract is obtained by extracting C. subavenium which is pulverized as particles with supercritical carbon dioxide fluid. The C. subavenium extract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, the C. subavenium extract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, the C. subavenium extract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.

Li; Jih-Heng

Huang; A-Mei

Chen; Chung-Yi

Lien; Pei-Jung

Liu; Chiung-Hui

Kaohsiung Medical University

Anti-human urothelial carcinoma of supercritical carbon dioxide extract of Cinnamomum subavenium, and the preparation process and uses

cinnamomum philippinense

antineoplásico

cinnamomum

anticancer

cinnamomum philippinense/antineoplásico

Anticancer composition containing herbal extract

Anti-human urothelial carcinoma of supercritical carbon dioxide extract of Cinnamomum subavenium, and the preparation process and uses

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