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[Evaluation of safety and pharmacotherapeutic efficacy of cycloferon in treatment of Astrakhan rickettsial fever].

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Clinicopathogenetic impact of cycloferon, an endogenous interferon inductor, on the process of Astrakhan rikettsial fever, its complications and outcomes was analysed. The treatment scheme with addition of cycloferon to the complex therapy was optimized. The specificity of the disease clinical

Progressive microvascular injury in liver and colorectal liver metastases following laser induced focal hyperthermia therapy.

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OBJECTIVE Focal hyperthermia by laser or radiofrequency is currently the preferred method for local ablation of liver tumors. The underlying mechanism of action of focal hyperthermia, in particular the relationship between the microvascular and tissue effect is uncertain and was investigated in a

Histochemical observations on muscle from normal and malignant hyperthermia-susceptible swine.

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A comparison was made of muscle from two locations in both the longissimus and the semitendinous muscles of normal and malignant hyperthermia-susceptible swine. Serial frozen sections were stained for alkali-stable adenosine triphosphatase (ATPase), phosphorylase, and the oxidative enzymes succinate

Focal hyperthermia produces progressive tumor necrosis independent of the initial thermal effects.

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Focal hyperthermia, produced using laser, radio frequency, and microwave, is used to treat liver tumors. The exact mechanisms of tissue destruction using focal hyperthermia are, however, unknown. Clinical and experimental studies suggest a progression of injury after cessation of the initial heat

Characterization of a cisplatin-resistant subline of murine RIF-1 cells and reversal of drug resistance by hyperthermia.

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The development of tumor cell drug resistance is a major obstacle which often leads to failure of cancer chemotherapy. Therefore, reversing the cell drug resistance would have important implications in cancer treatment. We have developed a cisplatin-resistant mouse tumor cell line from the radiation

Exposure to a hot environment can activate spinally projecting and nitrergic neurones in the lower brainstem in the rat.

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Reflex responses to hyperthermia include sweating, salivation and a redirection of blood flow from the viscera to the periphery, and involve changes in peripheral nerve activity mediated by the central nervous system (CNS), including specific areas of the ventral lower brainstem. The lower brainstem

The effect of temperature-control microwave on HELA and MG-63 cells.

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UNASSIGNED Hyperthermia has now been used to treat many kinds of solid malignancies. However, the applied thermal parameters about heat temperature and time varied all over the world, and no consensus about the optimal formula had been reached. Microwave ablation, as one of thermal ablation methods,

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