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Although systemic allergic laboratory tests for the quantification of allergen-specific serum IgE antibody have been widely used, in these tests a high titer of serum specific IgE does not necessarily indicate evidence of allergy. We evaluated the diagnostic value of the glass microfiber-based
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OBJECTIVE
Recently, a new commercial test for total tear immunoglobulin E (IgE), based on immunochromatography (Allerwatch), was developed. We examined the relation between the total IgE level in tears and specific serum IgE.
METHODS
A prospective, nonrandomized, cross-sectional study was conducted
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Laughter after viewing a humorous video "Modern Times" decreased Japanese cedar pollen-specific immunoglobulin E (IgE) and IgG4 levels, while it enhanced Japanese cedar pollen-specific IgA levels in tears of patients with atopic keratoconjunctivitis, while viewing a nonhumorous weather information
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OBJECTIVE
To investigate a method for determining antigen specific IgE antibodies in tears of patients with allergic keratoconjunctival disease.
METHODS
Antigen specific IgE antibodies to Japanese cedar pollen or Housedust-Mites in tears of patients with allergic conjunctival diseases were examined.
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Allergic conjunctival diseases caused by immediate hypersensitivity are classified into several subtypes, including seasonal or perennial allergic conjunctivitis, vernal keratoconjunctivitis (VKC), atopic karatoconjunctivitis, giant papillary conjunctivitis. The gold standard in treatment of
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We studied the effect of brain-derived neurotrophic factor (BDNF) on in vitro Japanese cedar pollen (JCP)-specific IgE production by mononuclear cells from atopic keratoconjunctivitis patients with JCP allergy. BDNF enhanced JCP-specific IgE production in a dose-dependent fashion in cultures of
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Asian dust storms frequently occur in northeast Asia and the dust occasionally even spreads as far as North America during spring. Asian dust can be harmful to human health and the environment, and thus has become one of the most serious problems for Asian countries. In the present study,
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OBJECTIVE
A new commercial immunochromatographic test (Allerwatch) has recently been developed for determining total immunoglobulin E (IgE). We previously reported on the use of this kit for analyzing tear fluid samples collected during the spring. In this study, we examined the relationship between
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