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10 resultados
Methods of treating cancer with herbacetin
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BACKGROUND OF THE INVENTION
Polyamines play important roles in normal and cancer cell growth. Elevated ornithine decarboxylase (ODC) activity is observed in neoplastic tissues suggesting that this enzyme is a target for cancer prevention or treatment. Difluoromethylomithine (DFMO), an approved FDA
Inhibition of ornithine aminotransferase for the treatment of proliferative disorders
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FIELD OF THE INVENTION
The invention relates to inhibition of ornithine aminotransferase (OAT) for suppression of tumor cells proliferation. More particularly, the invention relates to methods of treatment of proliferative disorders by inhibition of OAT, and further provides the use of OAT
Inhibition of ornithine aminotransferase for the treatment of proliferative disorders
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FIELD OF THE INVENTION
The invention relates to inhibition of ornithine aminotransferase (OAT) for suppression of tumor cells proliferation. More particularly, the invention relates to methods of treatment of proliferative disorders by inhibition of OAT, and further provides the use of OAT
Predictive markers for polyamine inhibitor cancer therapies
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BACKGROUND OF THE INVENTION
I. Field of the Invention
The present invention relates generally to the fields of cancer biology and medicine. More particularly, it concerns methods for the diagnosis, prevention, and treatment of carcinomas and risk factors thereof.
II. Description of Related
Agglutination of lymphocytes for diagnosing malignant tumor
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The invention relates to a process for the specific agglutination of lymphocytes of sensitized the peripheric blood, which is an important method in diagnostics for the detection of diseases accompanied by a changed agglutinability of the lymphocytes.
E. J. Field and E. A. Caspary observed a changed
Polyamine analogs that activate antizyme frameshifting
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CROSS-REFERENCE TO RELATED APPLICATIONS
Not applicable
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable
REFERENCE TO A COMPACT DISK APPENDIX
Not applicable
TECHNICAL FIELD
The present invention relates to novel polyamines, their synthesis and use in pharmacological,
Parenteral formulations for the inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to the field of prophylaxis and treatment of hypotension. Most particularly, the present invention proposes methods for the control and inhibition of hypotension or systemic shock through the administration of
Methods for the treatment of malignant disease in patients using citrulline containing amino acid solutions
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BACKGROUND OF THE INVENTION
Reference is made to Applicant's co-pending applications, Ser. No. 820,517, filed Jan. 17, 1986 and Ser. No. 002,890, filed Jan. 13, 1987.
FIELD OF THE INVENTION
The present invention relates to improved formulations and methods for the detection of malignant disease in a
Methods for the reduction of difluoromethylornithine associated toxicity
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BACKGROUND OF THE INVENTION
The present application is a continuation-in-part of Ser. No. 820,517, filed Jan. 17, 1986.
1. FIELD OF THE INVENTION
The present invention relates to improved formulations and methods for the detection of malignant disease in a patient. More particularly, the present
Methods and improved formulations for the determination and treatment of malignant disease in patients
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1. Field of the Invention
The present invention relates to improved formulations and methods for the detection of malignant disease in a patient. More particularly, the present invention is directed to formulations which augment tumor related increases in a patient's polyamine level and which
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